CD80

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CD80(英语:Cluster of Differentiation 80分化群80,也称为B7-1)是一个位于3号染色体的人类基因,属于免疫球蛋白超家族中的B7蛋白质家族[1],在树突状细胞、激活的B细胞巨噬细胞以及T细胞上表达[2],与CD86(也称为B7-2)形成共刺激信号[3]

参考文献[编辑]

  1. ^ Mir MA. Introduction to Costimulation and Costimulatory Molecules. Developing Costimulatory Molecules for Immunotherapy of Diseases (Elsevier). 2015: 1–43. ISBN 978-0-12-802585-7. doi:10.1016/b978-0-12-802585-7.00001-7. 
  2. ^ CD80 - T-lymphocyte activation antigen CD80 precursor - Homo sapiens (Human) - CD80 gene & protein. www.uniprot.org. [2021-06-09]. (原始内容存档于2024-12-13) (English). 
  3. ^ Peach RJ, Bajorath J, Naemura J, Leytze G, Greene J, Aruffo A, Linsley PS. Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28. The Journal of Biological Chemistry. September 1995, 270 (36): 21181–7. PMID 7545666. doi:10.1074/jbc.270.36.21181可免费查阅. 

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