CTLA-4
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Module:Infobox_gene第53行Lua错误：attempt to index field 'wikibase' (a nil value)
CTLA4又称CTLA-4（细胞毒性T淋巴细胞相关抗原4，cytotoxic T-lymphocyte-associated protein 4）或CD152（分化群152），是一种蛋白质受体[1]。CTLA-4蛋白由小鼠的Ctla4[2]和人类的CTLA4基因编码[3]。CTLA-4于1991年首次被发现[4]。
参考文献[编辑]
- ^ De-novo and acquired resistance to immune checkpoint targeting. The Lancet. Oncology. December 2017, 18 (12): e731–e741. PMID 29208439. doi:10.1016/s1470-2045(17)30607-1.
- ^ A new member of the immunoglobulin superfamily--CTLA-4. Nature. 1987, 328 (6127): 267–70. Bibcode:1987Natur.328..267B. PMID 3496540. doi:10.1038/328267a0.
- ^ Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains. European Journal of Immunology. December 1988, 18 (12): 1901–5. PMID 3220103. doi:10.1002/eji.1830181206.
- ^ Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science. November 1995, 270 (5238): 985–8. Bibcode:1995Sci...270..985W. JSTOR 2888113. PMID 7481803. doi:10.1126/science.270.5238.985.