TAX1BP1
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TAX1BP1(Tax1 binding protein 1,“Tax1结合蛋白1”)也称为CALCOCO3(Calcium-binding and coiled-coil domain-containing protein 3,“钙结合和卷曲螺旋区蛋白3”)是人类基因 TAX1BP1 编码的蛋白质[1],其名称来源于能和人类嗜T淋巴细胞病毒一型(HTLV-1)的蛋白Tax1结合[1]。
蛋白质的相互作用[编辑]
TAX1BP1蛋白与下列蛋白质进行互作:A20[2]和TRAF6[3],在与A20或TRAF6结合后抑制NF-κB转录因子激活。
参考文献[编辑]
- ^ 1.0 1.1 Entrez Gene: TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1.
- ^ De Valck D, Jin DY, Heyninck K, Van de Craen M, Contreras R, Fiers W, Jeang KT, Beyaert R. The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases. Oncogene. July 1999, 18 (29): 4182–90. PMID 10435631. doi:10.1038/sj.onc.1202787 可免费查阅.
- ^ Ling L, Goeddel DV. T6BP, a TRAF6-interacting protein involved in IL-1 signaling. Proceedings of the National Academy of Sciences of the United States of America. August 2000, 97 (17): 9567–72. Bibcode:2000PNAS...97.9567L. PMC 16905 可免费查阅. PMID 10920205. doi:10.1073/pnas.170279097 可免费查阅.