BD-1047
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| File:BD-1047 Structure.svg | |
| 临床资料 | |
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| 识别信息 | |
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| CAS号 | 138356-20-4 ☒ |
| PubChem CID | |
| IUPHAR/BPS | |
| ChemSpider | |
| UNII | |
| ChEMBL | |
| E编码 | {{#property:P628}} |
| CompTox Dashboard (EPA) |
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| ECHA InfoCard | {{#property:P2566}}Module:EditAtWikidata第29行Lua错误：attempt to index field 'wikibase' (a nil value) |
| 化学信息 | |
| 化学式 | C13H20Cl2N2 |
| 摩尔质量 | 275.22 g·mol−1 |
| 3D模型（JSmol） | |
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BD-1047是一种含氮有机氯化合物，化学式C
13H
20Cl
2N
2，能作为σ受体特别是σ1的选择性拮抗剂，可用于缓解神经性疼痛[1][2]。
参考文献[编辑]
- ^ Skuza G, Rogóz Z. Effect of BD 1047, a sigma1 receptor antagonist, in the animal models predictive of antipsychotic activity. Pharmacological Reports. 2006, 58 (5): 626–35. PMID 17085854.
- ^ Roh DH, Kim HW, Yoon SY, Seo HS, Kwon YB, Kim KW, Han HJ, Beitz AJ, Na HS, Lee JH. Intrathecal injection of the sigma(1) receptor antagonist BD1047 blocks both mechanical allodynia and increases in spinal NR1 expression during the induction phase of rodent neuropathic pain. Anesthesiology. November 2008, 109 (5): 879–89. PMID 18946301. doi:10.1097/ALN.0b013e3181895a83 可免费查阅.
