2-MDP

2-MDP
	File:2-MDP.svg
识别信息
	IUPAC命名法 3-amino-2-methyl-1,1-di(phenyl)propan-1-ol; ;
CAS号	14326-31-9 check; 14185-05-8 check
PubChem CID	26538;
ChemSpider	24719 check;
UNII	B6FTK35FGC; HCl: TJH732RKT9 check;
E编码	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Module:EditAtWikidata第29行Lua错误：attempt to index field 'wikibase' (a nil value);
ECHA InfoCard	{{#property:P2566}}Module:EditAtWikidata第29行Lua错误：attempt to index field 'wikibase' (a nil value)
化学信息
化学式	C16H19NO
摩尔质量	241.33 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES OC(c1ccccc1)(c2ccccc2)C(C)CN;
	InChI InChI=1S/C16H19NO/c1-13(12-17)16(18,14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,13,18H,12,17H2,1H3 check; Key:XGYCHIPEPHYUIH-UHFFFAOYSA-N check;

2-MDP也称为U-23807A是一种含氮有机化合物，分子式C
16H
19NO，为Upjohn研发的NMDA受体拮抗剂，在动物体内有苯环己哌啶（PCP）类似的功效，可作为解离剂和麻醉剂^[1]^[2]。

2-MDP可由二苯基甲酮为原料合成^[3]

参考文献[编辑]

^ Tang AH, Cangelosi AA, Code RA, Franklin SR. Phencyclidine-like behavioral effects of 2-methyl-3,3-diphenyl-3-propanolamine (2-MDP). Pharmacology, Biochemistry, and Behavior. February 1984, 20 (2): 209–213. PMID 6718449. S2CID 38908019. doi:10.1016/0091-3057(84)90244-2.
^ Blake JC, Davies SN, Church J, Martin D, Lodge D. 2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) selectively antagonises N-methyl-aspartate (NMA). Pharmacology, Biochemistry, and Behavior. January 1986, 24 (1): 23–25. PMID 3511477. S2CID 29762524. doi:10.1016/0091-3057(86)90038-9.
^ Moffett RB, Pickering TL. Central nervous system agents. 2. Synthesis of diphenyl primary and secondary aminopropanols. Journal of Medicinal Chemistry. November 1971, 14 (11): 1100–1106. PMID 5115211. doi:10.1021/jm00293a019.

识别信息
File:2-MDP.svg
IUPAC命名法 3-amino-2-methyl-1,1-di(phenyl)propan-1-ol
CAS号	14326-31-9 ^checkY 14185-05-8 ^checkY
PubChem CID	26538
ChemSpider	24719^checkY
UNII	B6FTK35FGC HCl: TJH732RKT9^checkY
E编码	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Module:EditAtWikidata第29行Lua错误：attempt to index field 'wikibase' (a nil value)
ECHA InfoCard	{{#property:P2566}}Module:EditAtWikidata第29行Lua错误：attempt to index field 'wikibase' (a nil value)
化学信息
化学式	C₁₆H₁₉NO
摩尔质量	241.33 g·mol⁻¹
3D模型（JSmol）	交互式图像
SMILES OC(c1ccccc1)(c2ccccc2)C(C)CN
InChI InChI=1S/C16H19NO/c1-13(12-17)16(18,14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,13,18H,12,17H2,1H3^checkY Key:XGYCHIPEPHYUIH-UHFFFAOYSA-N^checkY