TAX1BP1
跳至導覽
跳至搜尋
檢索資訊框的維基數據項目時發生錯誤
TAX1BP1（Tax1 binding protein 1，「Tax1結合蛋白1」）也稱為CALCOCO3（Calcium-binding and coiled-coil domain-containing protein 3，「鈣結合和捲曲螺旋區蛋白3」）是人類基因 TAX1BP1 編碼的蛋白質[1]，其名稱來源於能和人類嗜T淋巴球病毒一型（HTLV-1）的蛋白Tax1結合[1]。
蛋白質的相互作用[編輯]
TAX1BP1蛋白與下列蛋白質進行互作：A20[2]和TRAF6[3]，在與A20或TRAF6結合後抑制NF-κB轉錄因子活化。
參考文獻[編輯]
- ↑ 1.0 1.1 Entrez Gene: TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1.
- ↑ De Valck D, Jin DY, Heyninck K, Van de Craen M, Contreras R, Fiers W, Jeang KT, Beyaert R. The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases. Oncogene. July 1999, 18 (29): 4182–90. PMID 10435631. doi:10.1038/sj.onc.1202787 可免費查閱.
- ↑ Ling L, Goeddel DV. T6BP, a TRAF6-interacting protein involved in IL-1 signaling. Proceedings of the National Academy of Sciences of the United States of America. August 2000, 97 (17): 9567–72. Bibcode:2000PNAS...97.9567L. PMC 16905 可免費查閱. PMID 10920205. doi:10.1073/pnas.170279097 可免費查閱.
