TAX1BP1

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检索信息框的维基数据项目时发生错误

TAX1BP1Tax1 binding protein 1,“Tax1结合蛋白1”)也称为CALCOCO3Calcium-binding and coiled-coil domain-containing protein 3,“钙结合和卷曲螺旋区蛋白3”)是人类基因 TAX1BP1 编码的蛋白质[1],其名称来源于能和人类嗜T淋巴细胞病毒一型(HTLV-1)的蛋白Tax1结合[1]

蛋白质的相互作用[编辑]

TAX1BP1蛋白与下列蛋白质进行互作A20[2]TRAF6[3],在与A20或TRAF6结合后抑制NF-κB转录因子激活。

参考文献[编辑]

  1. 1.0 1.1 Entrez Gene: TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1. 
  2. De Valck D, Jin DY, Heyninck K, Van de Craen M, Contreras R, Fiers W, Jeang KT, Beyaert R. The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases. Oncogene. July 1999, 18 (29): 4182–90. PMID 10435631. doi:10.1038/sj.onc.1202787可免费查阅. 
  3. Ling L, Goeddel DV. T6BP, a TRAF6-interacting protein involved in IL-1 signaling. Proceedings of the National Academy of Sciences of the United States of America. August 2000, 97 (17): 9567–72. Bibcode:2000PNAS...97.9567L. PMC 16905可免费查阅. PMID 10920205. doi:10.1073/pnas.170279097可免费查阅.