SIB-1757

SIB-1757
	File:SIB-1757.svg
識別資訊
	IUPAC命名法 6-methyl-2-(phenylazo)-3-pyridinol; ;
CAS號	31993-01-8 check
PubChem CID	6849066;
ChemSpider	10654582;
E編碼	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Module:EditAtWikidata第29行Lua錯誤：attempt to index field 'wikibase' (a nil value);
ECHA InfoCard	{{#property:P2566}}Module:EditAtWikidata第29行Lua錯誤：attempt to index field 'wikibase' (a nil value)
化學資訊
化學式	C12H11N3O
摩爾質量	213.24 g·mol−1
3D模型（JSmol）	交互式圖像;
	SMILES Oc1ccc(C)nc1\N=N\c2ccccc2;
	InChI InChI=1S/C12H11N3O/c1-9-7-8-11(16)12(13-9)15-14-10-5-3-2-4-6-10/h2-8,16H,1H3/b15-14+; Key:LOCPVWIREQIGNQ-CCEZHUSRSA-N;

SIB-1757是一種有機化合物，分子式C₁₂H₁₁N₃O，帶有偶氮基團，可作為代謝型穀氨酸受體亞型mGluR₅的受體拮抗劑^[1]，在動物實驗中存在抗痛覺過敏作用^[2]。

參考文獻[編輯]

^ Varney MA, Cosford ND, Jachec C, Rao SP, Sacaan A, Lin FF, Bleicher L, Santori EM, Flor PJ, Allgeier H, Gasparini F, Kuhn R, Hess SD, Veliçelebi G, Johnson EC. SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5. The Journal of Pharmacology and Experimental Therapeutics. July 1999, 290 (1): 170–81. PMID 10381773.
^ Dogrul A, Ossipov MH, Lai J, Malan TP, Porreca F. Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR(5)) antagonist, in experimental neuropathic pain in rats. Neuroscience Letters. October 2000, 292 (2): 115–8. PMID 10998562. doi:10.1016/S0304-3940(00)01458-0.

識別資訊
File:SIB-1757.svg
IUPAC命名法 6-methyl-2-(phenylazo)-3-pyridinol
CAS號	31993-01-8 ^checkY
PubChem CID	6849066
ChemSpider	10654582
E編碼	{{#property:P628}}
CompTox Dashboard (EPA)	{{#property:P3117}}Module:EditAtWikidata第29行Lua錯誤：attempt to index field 'wikibase' (a nil value)
ECHA InfoCard	{{#property:P2566}}Module:EditAtWikidata第29行Lua錯誤：attempt to index field 'wikibase' (a nil value)
化學資訊
化學式	C₁₂H₁₁N₃O
摩爾質量	213.24 g·mol⁻¹
3D模型（JSmol）	交互式圖像
SMILES Oc1ccc(C)nc1\N=N\c2ccccc2
InChI InChI=1S/C12H11N3O/c1-9-7-8-11(16)12(13-9)15-14-10-5-3-2-4-6-10/h2-8,16H,1H3/b15-14+ Key:LOCPVWIREQIGNQ-CCEZHUSRSA-N