GRIA1
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GRIA1(英语：glutamate receptor, ionotropic, AMPA 1)化学式为：C5005H7819O1704N1231S37[1]，是由GRIA1 基因编码的蛋白质。[2][3]
交互作用[编辑]
GRIA1与以下蛋白质有交互作用:
参见[编辑]
参考[编辑]
- ^ Expasy - ProtParam. web.expasy.org｜基于一个通用的成熟双碱基复合型糖链模型（GlcNAc₄Man₃Gal₂Fuc₁Neu5Ac₂，单链净增长C₉₀H₁₄₆N₆O₆₅），在假设其 6个 N-糖基化位点均被完全修饰且形成 2个二硫键的理论模型下，该受体成熟形式的化学式为C₅₀₀₅H₇₈₁₉O₁₇₀₄N₁₂₃₁S₃₇. [2026-05-29].
- ^ Puckett, C; Gomez, C M; Korenberg, J R; Tung, H; Meier, T J; Chen, X N; Hood, L. Molecular cloning and chromosomal localization of one of the human glutamate receptor genes.. Proceedings of the National Academy of Sciences. 1991-09, 88 (17): 7557-7561. ISSN 0027-8424. PMC 52340 可免费查阅. PMID 1652753. doi:10.1073/pnas.88.17.7557 （English）.
- ^ McNamara, Jo; Eubanks, Jh; McPherson, Jd; Wasmuth, Jj; Evans, Ga; Heinemann, Sf. Chromosomal localization of human glutamate receptor genes. The Journal of Neuroscience. 1992-07-01, 12 (7): 2555-2562. ISSN 0270-6474. PMC 6575855 可免费查阅. PMID 1319477. doi:10.1523/JNEUROSCI.12-07-02555.1992 （English）.
- ^ Gardoni, Fabrizio; Mauceri, Daniela; Fiorentini, Chiara; Bellone, Camilla; Missale, Cristina; Cattabeni, Flaminio; Luca, Monica Di. CaMKII-dependent Phosphorylation Regulates SAP97/NR2A Interaction *. Journal of Biological Chemistry. 2003-11-07, 278 (45): 44745–44752 [2025-01-30]. ISSN 0021-9258. PMID 12933808. doi:10.1074/jbc.M303576200. （原始内容存档于2024-12-21） （English）.
- ^ Leonard, A. Soren; Davare, Monika A.; Horne, M. C.; Garner, Craig C.; Hell, Johannes W. SAP97 Is Associated with the α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor GluR1 Subunit *. Journal of Biological Chemistry. 1998-07-31, 273 (31): 19518–19524. ISSN 0021-9258. PMID 9677374. doi:10.1074/jbc.273.31.19518 （English）.
- ^ Sans, Nathalie; Racca, Claudia; Petralia, Ronald S.; Wang, Ya-Xian; McCallum, Jennifer; Wenthold, Robert J. Synapse-Associated Protein 97 Selectively Associates with a Subset of AMPA Receptors Early in their Biosynthetic Pathway. The Journal of Neuroscience. 2001-10-01, 21 (19): 7506-7516. ISSN 0270-6474. PMC 6762903 可免费查阅. PMID 11567040. doi:10.1523/JNEUROSCI.21-19-07506.2001 （English）.
- ^ Shen, Lei; Liang, Feng; Walensky, Loren D.; Huganir, Richard L. Regulation of AMPA Receptor GluR1 Subunit Surface Expression by a 4.1N-Linked Actin Cytoskeletal Association. The Journal of Neuroscience. 2000-11-01, 20 (21): 7932-7940. ISSN 0270-6474. PMC 6772741 可免费查阅. PMID 11050113. doi:10.1523/JNEUROSCI.20-21-07932.2000 （English）.
- ^ Kohda, Kazuhisa; Kamiya, Yoshinori; Matsuda, Shinji; Kato, Kunio; Umemori, Hisashi; Yuzaki, Michisuke. Heteromer formation of δ2 glutamate receptors with AMPA or kainate receptors. Molecular Brain Research. 2003-01-31, 110 (1): 27–37 [2025-01-30]. ISSN 0169-328X. PMID 12573530. doi:10.1016/S0169-328X(02)00561-2. （原始内容存档于2025-01-04）.
深入阅读[编辑]
- Sun W, Ferrer-Montiel AV, Schinder AF, McPherson JP, Evans GA, Montal M. Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors.. Proc. Natl. Acad. Sci. U.S.A. 1992, 89 (4): 1443–7. PMC 48467 可免费查阅. PMID 1311100. doi:10.1073/pnas.89.4.1443.
- Potier MC, Spillantini MG, Carter NP. The human glutamate receptor cDNA GluR1: cloning, sequencing, expression and localization to chromosome 5.. DNA Seq. 1992, 2 (4): 211–8. PMID 1320959. doi:10.3109/10425179209020805.
- Yakel JL, Vissavajjhala P, Derkach VA, Brickey DA, Soderling TR. Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors.. Proc. Natl. Acad. Sci. U.S.A. 1995, 92 (5): 1376–80. PMC 42522 可免费查阅. PMID 7877986. doi:10.1073/pnas.92.5.1376.
- Eastwood SL, Burnet PW, Beckwith J, Kerwin RW, Harrison PJ. AMPA glutamate receptors and their flip and flop mRNAs in human hippocampus.. NeuroReport. 1994, 5 (11): 1325–8. PMID 7919190. doi:10.1097/00001756-199406270-00007.
- Roche KW, Raymond LA, Blackstone C, Huganir RL. Transmembrane topology of the glutamate receptor subunit GluR6.. J. Biol. Chem. 1994, 269 (16): 11679–82. PMID 8163463.
- McLaughlin DP, Cheetham ME, Kerwin RW. Expression of alternatively-spliced glutamate receptors in human hippocampus.. Eur. J. Pharmacol. 1993, 244 (1): 89–92. PMID 8420792. doi:10.1016/0922-4106(93)90062-E.
- Roche KW, O'Brien RJ, Mammen AL, Bernhardt J, Huganir RL. Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit.. Neuron. 1996, 16 (6): 1179–88. PMID 8663994. doi:10.1016/S0896-6273(00)80144-0.
- Brakeman PR, Lanahan AA, O'Brien R, Roche K, Barnes CA, Huganir RL, Worley PF. Homer: a protein that selectively binds metabotropic glutamate receptors.. Nature. 1997, 386 (6622): 284–8. PMID 9069287. doi:10.1038/386284a0.
- Barria A, Derkach V, Soderling T. Identification of the Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate-type glutamate receptor.. J. Biol. Chem. 1998, 272 (52): 32727–30. PMID 9407043. doi:10.1074/jbc.272.52.32727.
- Ripellino JA, Neve RL, Howe JR. Expression and heteromeric interactions of non-N-methyl-D-aspartate glutamate receptor subunits in the developing and adult cerebellum.. Neuroscience. 1998, 82 (2): 485–97. PMID 9466455. doi:10.1016/S0306-4522(97)00296-0.
- Leonard AS, Davare MA, Horne MC, Garner CC, Hell JW. SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit.. J. Biol. Chem. 1998, 273 (31): 19518–24. PMID 9677374. doi:10.1074/jbc.273.31.19518.
- Xiao B, Tu JC, Petralia RS, Yuan JP, Doan A, Breder CD, Ruggiero A, Lanahan AA, Wenthold RJ, Worley PF. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.. Neuron. 1998, 21 (4): 707–16. PMID 9808458. doi:10.1016/S0896-6273(00)80588-7.
- Montague AA, Greer CA. Differential distribution of ionotropic glutamate receptor subunits in the rat olfactory bulb.. J. Comp. Neurol. 1999, 405 (2): 233–46. PMID 10023812. doi:10.1002/(SICI)1096-9861(19990308)405:2<233::AID-CNE7>3.0.CO;2-A.
- Leuschner WD, Hoch W. Subtype-specific assembly of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits is mediated by their n-terminal domains.. J. Biol. Chem. 1999, 274 (24): 16907–16. PMID 10358037. doi:10.1074/jbc.274.24.16907.
- Shi SH, Hayashi Y, Petralia RS, Zaman SH, Wenthold RJ, Svoboda K, Malinow R. Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation.. Science. 1999, 284 (5421): 1811–6. PMID 10364548. doi:10.1126/science.284.5421.1811.
- Rubio ME, Wenthold RJ. Calnexin and the immunoglobulin binding protein (BiP) coimmunoprecipitate with AMPA receptors.. J. Neurochem. 1999, 73 (3): 942–8. PMID 10461883. doi:10.1046/j.1471-4159.1999.0730942.x.
- Stinehelfer S, Vruwink M, Burette A. Immunolocalization of mGluR1alpha in specific populations of local circuit neurons in the cerebral cortex.. Brain Res. 2000, 861 (1): 37–44. PMID 10751563. doi:10.1016/S0006-8993(00)01952-1.