CXCL9
跳至導覽
跳至搜尋
Template:Infobox gene CXCL9(Template:Langx)化學式為C509H877O148N159S4[1]是一小分子的細胞因子屬於CXC趨化因子家族,又被稱作「干擾素伽瑪誘導的單核細胞因子」(Monokine induced by gamma interferon, MIG)[2]。CXCL9是T細胞趨化因子[2]。干擾素伽瑪誘導CXCL9的表達。人類的CXCL9與CXCL10,CXCL11的基因相鄰聚集在第四染色體上[3]。CXCL9,CXCL10, CXCL11結合趨化因子受體CXCR3而起其細胞趨化作用[4][5]。
參見[編輯]
參考文獻[編輯]
- ↑ Template:Cite web
- ↑ 2.0 2.1 Liao F, Rabin RL, Yannelli JR, Koniaris LG, Vanguri P, Farber JM. Human Mig chemokine: biochemical and functional characterization. J Exp Med. 1995 Nov 1;182(5):1301-14.
- ↑ Lee HH, Farber JM. Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine "mini-cluster". Cytogenet Cell Genet. 1996;74(4):255-8.
- ↑ Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, Clark-Lewis I, Baggiolini M, Moser B. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 1996 Sep 1;184(3):963-9.
- ↑ Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS, DeMartino JA. Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors. J Biol Chem. 1998 Jul 17;273(29):18288-91.