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{{Drugbox
| IUPAC_name = 2-(2,4-dichlorophenyl)-N-[(1S,2S)-2-(dimethylamino)cyclohexyl]-N-methylacetamide
| image = U-48800_structure.png


| tradename =
| pregnancy_AU = 
| pregnancy_category =
| legal_AU = 
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =


| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =


| CAS_number = 2370977-17-4
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = C1X8MF00M5
| ATC_suffix =
| PubChem = 137700072
| DrugBank =
| ChemSpiderID =
| ChEMBL =


| C=17 | H=24 | Cl=2 | N=2 | O=1
| smiles = CN(C)[C@H]1CCCC[C@@H]1N(C)C(=O)CC2=C(C=C(C=C2)Cl)Cl
| StdInChI = 1S/C17H24Cl2N2O/c1-20(2)15-6-4-5-7-16(15)21(3)17(22)10-12-8-9-13(18)11-14(12)19/h8-9,11,15-16H,4-7,10H2,1-3H3/t15-,16-/m0/s1
| StdInChIKey = FKUWIGXXBMULOI-HOTGVXAUSA-N
}}
'''{{PAGENAME}}'''是一种[[氮化合物|含氮]][[有机氯化合物]]，化学式[[C17H24Cl2N2O|{{chem2|C17H24Cl2N2O}}]]，可作为[[類阿片]][[镇痛药]]，由[[Upjohn]]公司研发<ref name="pmid31424163">{{cite journal | vauthors = Gampfer TM, Richter LH, Schäper J, Wagmann L, Meyer MR | title = Toxicokinetics and analytical toxicology of the abused opioid U-48800 - in vitro metabolism, metabolic stability, isozyme mapping, and plasma protein binding | journal = Drug Testing and Analysis | volume = 11 | issue = 10 | pages = 1572–1580 | date = October 2019 | pmid = 31424163 | doi = 10.1002/dta.2683 | url = }}</ref><ref name="pmid33238449">{{cite journal | vauthors = Baumann MH, Tocco G, Papsun DM, Mohr AL, Fogarty MF, Krotulski AJ | title = U-47700 and Its Analogs: Non-Fentanyl Synthetic Opioids Impacting the Recreational Drug Market | journal = Brain Sciences | volume = 10 | issue = 11 | date = November 2020 | page = 895 | pmid = 33238449 | pmc = 7700279 | doi = 10.3390/brainsci10110895 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Fogarty MF, Mohr AL, Papsun DM, Logan BK | title = Analysis of the Illicit Opioid U-48800 and Related Compounds by LC-MS-MS and Case Series of Fatalities Involving U-48800 | journal = Journal of Analytical Toxicology | volume = 46 | issue = 1 | pages = 17–24 | date = February 2022 | doi = 10.1093/jat/bkaa180 | pmid = 33237987 }}</ref><ref>{{cite journal | vauthors = Otte L, Wilde M, Auwärter V, Grafinger KE | title = Investigation of the μ- and κ-opioid receptor activation by eight new synthetic opioids using the [<sup>35</sup> S]-GTPγS assay: U-47700, isopropyl U-47700, U-49900, U-47931E, N-methyl U-47931E, U-51754, U-48520, and U-48800 | journal = Drug Testing and Analysis | volume = 14 | issue = 7 | pages = 1187–1199 | date = July 2022 | doi = 10.1002/dta.3238 | pmid = 35142070 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Amend N, Thiermann H, Worek F, Wille T | title = A pharmacologically pre-contracted smooth muscle bowel model for the study of highly-potent opioid receptor agonists and antagonists | journal = Toxicology Letters | volume = 382 | pages = 41–46 | date = June 2023 | doi = 10.1016/j.toxlet.2023.05.010 | pmid = 37245850 | doi-access = free }}</ref> 。

==参考文献==
{{reflist}}

[[Category:苯甲酰胺]]
[[Category:合成阿片类物质]]
[[Category:Μ-阿片激动剂]]

U-48800 - 版本历史

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