https://arolstar52-zhtest.hf.space/index.php?action=history&feed=atom&title=Template%3APBB%2F1565 2026-07-19T18:23:38Z 本wiki上该页面的版本历史 MediaWiki 1.43.9 https://arolstar52-zhtest.hf.space/index.php?title=Template:PBB/1565&diff=2615188&oldid=prev 2015-09-14T13:33:29Z

<p>//Edit via Wikiplus</p> <p><b>新页面</b></p><div>{{GNF_Protein_box<br /> | Name = Cytochrome P450, family 2, subfamily D, polypeptide 6<br /> | image = CYP2D6_structure.png<br /> | image_source = [[Protein_Data_Bank|PDB]]基于2f9q的渲染图<br /> | PDB = {{PDB2|2F9Q}}, {{PDB2|3QM4}}, {{PDB2|3TBG}}, {{PDB2|3TDA}}, {{PDB2|4WNT}}, {{PDB2|4WNU}}, {{PDB2|4WNV}}, {{PDB2|4WNW}}<br /> | HGNCid = 2625<br /> | MGIid = 1929474<br /> | Symbol = CYP2D6<br /> | AltSymbols =; CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; P450-DB1; P450C2D; P450DB1<br /> | IUPHAR = <br /> | ChEMBL = <br /> | OMIM = 124030<br /> | ECnumber = 1.14.14.1<br /> | Homologene = 133550<br /> | GeneAtlas_image1 = PBB_GE_CYP2D6_207498_s_at_tn.png<br /> | GeneAtlas_image2 = PBB_GE_CYP2D6_215809_at_tn.png<br /> | GeneAtlas_image3 = <br /> | Protein_domain_image = <br /> | Function = {{GNF_GO|id=GO:0004497 |text = monooxygenase activity}} {{GNF_GO|id=GO:0005506 |text = iron ion binding}} {{GNF_GO|id=GO:0008144 |text = drug binding}} {{GNF_GO|id=GO:0008392 |text = arachidonic acid epoxygenase activity}} {{GNF_GO|id=GO:0008395 |text = steroid hydroxylase activity}} {{GNF_GO|id=GO:0016491 |text = oxidoreductase activity}} {{GNF_GO|id=GO:0016712 |text = oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen}} {{GNF_GO|id=GO:0019825 |text = oxygen binding}} {{GNF_GO|id=GO:0020037 |text = heme binding}} {{GNF_GO|id=GO:0070330 |text = aromatase activity}}<br /> | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0005789 |text = endoplasmic reticulum membrane}}<br /> | Process = {{GNF_GO|id=GO:0006805 |text = xenobiotic metabolic process}} {{GNF_GO|id=GO:0008202 |text = steroid metabolic process}} {{GNF_GO|id=GO:0009804 |text = coumarin metabolic process}} {{GNF_GO|id=GO:0009820 |text = alkaloid metabolic process}} {{GNF_GO|id=GO:0009822 |text = alkaloid catabolic process}} {{GNF_GO|id=GO:0016098 |text = monoterpenoid metabolic process}} {{GNF_GO|id=GO:0017144 |text = drug metabolic process}} {{GNF_GO|id=GO:0019369 |text = arachidonic acid metabolic process}} {{GNF_GO|id=GO:0033076 |text = isoquinoline alkaloid metabolic process}} {{GNF_GO|id=GO:0042737 |text = drug catabolic process}} {{GNF_GO|id=GO:0042738 |text = exogenous drug catabolic process}} {{GNF_GO|id=GO:0044281 |text = small molecule metabolic process}} {{GNF_GO|id=GO:0046483 |text = heterocycle metabolic process}} {{GNF_GO|id=GO:0051100 |text = negative regulation of binding}} {{GNF_GO|id=GO:0055114 |text = oxidation-reduction process}} {{GNF_GO|id=GO:0070989 |text = oxidative demethylation}} {{GNF_GO|id=GO:0090350 |text = negative regulation of cellular organofluorine metabolic process}}<br /> | Hs_EntrezGene = 1565<br /> | Hs_Ensembl = ENSG00000100197<br /> | Hs_RefseqmRNA = NM_000106<br /> | Hs_RefseqProtein = NP_000097<br /> | Hs_GenLoc_db = hg38<br /> | Hs_GenLoc_chr = 22<br /> | Hs_GenLoc_start = 42126499<br /> | Hs_GenLoc_end = 42130906<br /> | Hs_Uniprot = P10635<br /> | Mm_EntrezGene = 13101<br /> | Mm_Ensembl = ENSMUSG00000094806<br /> | Mm_RefseqmRNA = NM_010005<br /> | Mm_RefseqProtein = NP_034135<br /> | Mm_GenLoc_db = <br /> | Mm_GenLoc_chr = 15<br /> | Mm_GenLoc_start = 82402846<br /> | Mm_GenLoc_end = 82407194<br /> | Mm_Uniprot = P24456<br /> | path = PBB/1565<br /> }}</div>

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