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{{PBB|geneid=259296}}
'''味觉感受器，类型2，成员50，TAS2R50''' 是一个人类基因组中''TAS2R50''基因编码的蛋白质，是苦味味觉感受器的一员。<ref name="pmid12379855">{{cite journal | author = Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W | title = The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides | journal = Nat Genet | volume = 32 | issue = 3 | pages = 397–401 | pmid = 12379855 | pmc = | doi = 10.1038/ng1014 |date=Oct 2002}}</ref><ref name="pmid12584440">{{cite journal | author = Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ | title = Identification and characterization of human taste receptor genes belonging to the TAS2R family | journal = Cytogenet Genome Res | volume = 98 | issue = 1 | pages = 45–53 | pmid = 12584440 | pmc = | doi = 10.1159/000068546 |date=Feb 2003}}</ref><ref name="pmid16175505">{{cite journal | author = Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM, Iakoubova OA, Pullinger CR, Cassano J, Aouizerat BE, Fenwick RG, Reitz RE, Catanese JJ, Leong DU, Zellner C, Sninsky JJ, Topol EJ, Devlin JJ, Kane JP | title = Identification of Four Gene Variants Associated with Myocardial Infarction | journal = Am J Hum Genet | volume = 77 | issue = 4 | pages = 596–605 | pmid = 16175505 | pmc = 1275608 | doi = 10.1086/491674 |date=Sep 2005}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TAS2R50 taste receptor, type 2, member 50| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=259296| accessdate = }}</ref>

==另见==
* [[味觉感受器]]

==参考文献==
{{reflist}}

==扩展阅读==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Margolskee RF |title=Molecular mechanisms of bitter and sweet taste transduction | url=https://archive.org/details/sim_journal-of-biological-chemistry_2002-01-04_277_1/page/n13 |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 1–4 |year= 2002 |pmid= 11696554 |doi= 10.1074/jbc.R100054200 }}
*{{cite journal | author=Montmayeur JP, Matsunami H |title=Receptors for bitter and sweet taste |journal=Curr. Opin. Neurobiol. |volume=12 |issue= 4 |pages= 366–71 |year= 2002 |pmid= 12139982 |doi=10.1016/S0959-4388(02)00345-8 }}
*{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 | author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
*{{cite journal | author=Zhang Y |title=Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways |journal=Cell |volume=112 |issue= 3 |pages= 293–301 |year= 2003 |pmid= 12581520 |doi=10.1016/S0092-8674(03)00071-0 | author2=Hoon MA | author3=Chandrashekar J | display-authors=3 | last4=Mueller | first4=Ken L. | last5=Cook | first5=Boaz | last6=Wu | first6=Dianqing | last7=Zuker | first7=Charles S. | last8=Ryba | first8=Nicholas J.P. }}
*{{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 | author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
*{{cite journal | author=Fischer A, Gilad Y, Man O, Pääbo S |title=Evolution of bitter taste receptors in humans and apes | url=https://archive.org/details/sim_molecular-biology-and-evolution_2005-03_22_3/page/432 |journal=Mol. Biol. Evol. |volume=22 |issue= 3 |pages= 432–6 |year= 2005 |pmid= 15496549 |doi= 10.1093/molbev/msi027 }}
*{{cite journal | author=Go Y, Satta Y, Takenaka O, Takahata N |title=Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates |journal=Genetics |volume=170 |issue= 1 |pages= 313–26 |year= 2006 |pmid= 15744053 |doi= 10.1534/genetics.104.037523 | pmc=1449719 }}
}}
{{refend}}

{{G蛋白偶联受体}}

[[Category:G蛋白偶联受体]]

TAS2R50 - 版本历史

imported>InternetArchiveBot：​Add 1 book for verifiability (20251017sim)) #IABot (v2.0.9.5) (GreenC bot

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