https://arolstar52-zhtest.hf.space/index.php?action=history&feed=atom&title=T-0156
T-0156 - 版本历史
2026-07-19T02:24:29Z
本wiki上该页面的版本历史
MediaWiki 1.43.9
https://arolstar52-zhtest.hf.space/index.php?title=T-0156&diff=3613039&oldid=prev
2023年4月1日 (六) 15:19 imported>微肿头龙
2023-04-01T15:19:01Z
<p></p>
<p><b>新页面</b></p><div>{{Chembox<br />
| ImageFile = T-0156.svg<br />
| ImageSize = 225<br />
| ImageAlt = <br />
| IUPACName = Methyl 2-[(2-methylpyridin-4-yl)methyl]-1-oxo-8-(pyrimidin-2-ylmethoxy)-4-(3,4,5-trimethoxyphenyl)-2,7-naphthyridine-3-carboxylate<br />
| OtherNames = T0156; Tocris-1676<br />
<br />
| Section1 = {{Chembox Identifiers<br />
| IUPHAR_ligand = 5275<br />
| CASNo = 324572-92-1<br />
| CASNo_Ref = {{cascite|correct|CAS}}<br />
| PubChem = 5368<br />
| PubChem1 = 9852041<br />
| PubChem1_Comment = [[盐酸盐]]<br />
| ChemSpiderID = 5175<br />
| ChemSpiderID1 = 8027754<br />
| ChemSpiderID1_Comment = (盐酸盐)<br />
| InChI=1S/C31H29N5O7/c1-18-13-19(7-11-32-18)16-36-27(31(38)42-5)25(20-14-22(39-2)28(41-4)23(15-20)40-3)21-8-12-35-29(26(21)30(36)37)43-17-24-33-9-6-10-34-24/h6-15H,16-17H2,1-5H3<br />
| InChIKey= JEMJAABFSYOLAP-UHFFFAOYSA-N<br />
| SMILES = CC1=NC=CC(=C1)CN2C(=C(C3=C(C2=O)C(=NC=C3)OCC4=NC=CC=N4)C5=CC(=C(C(=C5)OC)OC)OC)C(=O)OC<br />
}}<br />
<br />
| Section2 = {{Chembox Properties<br />
| C=31 | H=29 | N=5 | O=7<br />
| Appearance =<br />
| Density =<br />
| MeltingPt =<br />
| BoilingPt =<br />
| Solubility =<br />
}}<br />
<br />
| Section3 = {{Chembox Hazards<br />
| MainHazards =<br />
| FlashPt =<br />
| AutoignitionPt =<br />
}}<br />
}}<br />
'''T-0156'''，分子式C<sub>31</sub>H<sub>29</sub>N<sub>5</sub>O<sub>7</sub>，但通常以[[盐酸盐]]的形式存在，是一种[[第五型磷酸二酯酶抑制劑|第五型磷酸二酯酶]]（PDE5）[[酶抑制剂|抑制剂]]<ref>{{cite journal | last1 = Parlak | first1 = A | last2 = Yildirim | first2 = S | last3 = Bagcivan | first3 = I | last4 = Durmus | first4 = N | title = Role of New Agents Affecting NO/cGMP Pathway on Ovalbumin-Sensitized Guinea Pig Trachea | journal = Experimental Lung Research | date = October 2012 | volume = 38 | issue = 8 | pages = 420–6 | doi = 10.3109/01902148.2012.719281 | pmid = 23030645| s2cid = 22720639 }}</ref><ref>{{cite journal | last1 = Santos | first1 = AI | last2 = Carreira | first2 = BP | last3 = Nobre | first3 = RJ | last4 = Carvalho | first4 = CM | last5 = Araújo | first5 = IM | title = Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5 | journal = Stem Cells International | date = 2014 | volume = 2014 | pages = 878397 | doi = 10.1155/2014/878397 | pmid = 24550991 | pmc = 3914480}}</ref>。<br />
== 參考資料 ==<br />
{{Reflist}}<br />
<br />
== 外部連結 ==<br />
{{磷酸二酯酶抑制药}}<br />
<br />
[[Category:PDE5抑制剂]]<br />
[[Category:内酰胺]]<br />
[[Category:苯甲醚]]<br />
[[Category:萘啶]]</div>
imported>微肿头龙