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{{Infobox_gene}}

'''STAT1'''是[[转录因子]]中[[信号转导及转录激活蛋白]]（STAT蛋白）家族的一员。化學式為：C3920H6153O1172N1057S28P2

STAT1涉及[[I型干扰素|I型]]、[[II型干扰素|II型]]或[[III型干扰素|III型]][[干扰素]]激活基因的正调控。在[[干扰素伽玛|干扰素-γ]]刺激下，STAT1会组成同源二聚体或与[[STAT3]]组成异二聚体结合到'''GAS'''（Interferon-'''G'''amma-'''A'''ctivated '''S'''equence，干扰素γ激活序列）启动子上；而在[[I型干扰素|干扰素-α或干扰素-β]]刺激下，STAT1会与[[STAT2]]组成异二聚体结合到'''ISRE'''（'''I'''nterferon-'''S'''timulated '''R'''esponse '''E'''lement，干扰素激活反应元件）启动子上<ref>{{cite journal |author=Michael G. Katze |title=Viruses and interferon: a fight for supremacy |journal=Nature Reviews Immunology |volume=2 |pages=675–87 |year=2002 |pmid=12209136 |doi=10.1038/nri888 |issue=9 |author2=Yupeng He & Michael Gale |display-authors=2 |last3=Gale |first3=Michael}}</ref>。在这两种情况下，STAT二聚体与启动子的结合都会导致'''ISG'''（'''I'''nterferon-'''S'''timulated '''G'''enes，干扰素激活基因）的表达。

STAT1可由[[二烯丙基二硫]]诱导表达<ref>{{cite journal | author=Lu HF, Yang JS, Lin YT, Tan TW, Ip SW, Li YC, Tsou MF, Chung JG. |title=Diallyl disulfide induced signal transducer and activator of transcription 1 expression in human colon cancer colo 205 cells using differential display RT-PCR|journal=Cancer Genomics Proteomics. |volume=4 |issue= 2 |pages= 93–7 |year= 2007 |pmid= 17804871 |doi= }}</ref>

==相互作用==
STAT1能与下列蛋白质发生[[蛋白質交互作用|相互作用]]：
{{div col|colwidth=16em}}
*{{le|蛋白激酶R|Protein kinase R}}<ref name=pmid9135145>{{cite journal |last=Wong |first=A H |authorlink= |coauthors=Tam N W, Yang Y L, Cuddihy A R, Li S, Kirchhoff S, Hauser H, Decker T, Koromilas A E |date=March 1997 |title=Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways |journal=EMBO J. |volume=16 |issue=6 |pages=1291–304 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 9135145 |doi = 10.1093/emboj/16.6.1291 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_embo-journal_1997-03-17_16_6/page/1290| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1169727 }}</ref><ref name=pmid11278865>{{cite journal |last=Wong |first=A H |authorlink= |coauthors=Durbin J E, Li S, Dever T E, Decker T, Koromilas A E |date=April 2001 |title=Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR |journal=J. Biol. Chem. |volume=276 |issue=17 |pages=13727–37 |publisher= |location = United States| issn = 0021-9258| pmid = 11278865 |doi = 10.1074/jbc.M011240200 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_2001-04-27_276_17/page/13726| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
*[[Src (基因)|Src]]<ref name=pmid10358079>{{cite journal |last=Olayioye |first=M A |authorlink= |coauthors=Beuvink I, Horsch K, Daly J M, Hynes N E |date=June 1999 |title=ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases |journal=J. Biol. Chem. |volume=274 |issue=24 |pages=17209–18 |publisher= |location = United States| issn = 0021-9258| pmid = 10358079 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_1999-06-11_274_24/page/17208| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.274.24.17209 }}</ref><ref name=pmid9344858>{{cite journal |last=Cirri |first=P |authorlink= |coauthors=Chiarugi P, Marra F, Raugei G, Camici G, Manao G, Ramponi G |date=October 1997 |title=c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells |journal=Biochem. Biophys. Res. Commun. |volume=239 |issue=2 |pages=493–7 |publisher= |location = United States| issn = 0006-291X| pmid = 9344858 |doi = 10.1006/bbrc.1997.7493 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
*[[IRF1]]<ref name=pmid10764778>{{cite journal |last=Chatterjee-Kishore |first=M |authorlink= |coauthors=van Den Akker F, Stark G R |date=July 2000 |title=Adenovirus E1A down-regulates LMP2 transcription by interfering with the binding of stat1 to IRF1 |journal=J. Biol. Chem. |volume=275 |issue=27 |pages=20406–11 |publisher= |location = United States| issn = 0021-9258| pmid = 10764778 |doi = 10.1074/jbc.M001861200 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_2000-07-07_275_27/page/20406| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
*[[STAT3]]<ref name=pmid11594781>{{cite journal |last=Gunaje |first=J J |authorlink= |coauthors=Bhat G J |date=October 2001 |title=Involvement of tyrosine phosphatase PTP1D in the inhibition of interleukin-6-induced Stat3 signaling by alpha-thrombin |journal=Biochem. Biophys. Res. Commun. |volume=288 |issue=1 |pages=252–7 |publisher= |location = United States| issn = 0006-291X| pmid = 11594781 |doi = 10.1006/bbrc.2001.5759 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid11722592>{{cite journal |last=Spiekermann |first=K |authorlink= |coauthors=Biethahn S, Wilde S, Hiddemann W, Alves F |date=August 2001 |title=Constitutive activation of STAT transcription factors in acute myelogenous leukemia |journal=Eur. J. Haematol. |volume=67 |issue=2 |pages=63–71 |publisher= |location = Denmark| issn = 0902-4441| pmid = 11722592 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid12070153>{{cite journal |last=Xia |first=Ling |authorlink= |coauthors=Wang Lijuan, Chung Alicia S, Ivanov Stanimir S, Ling Mike Y, Dragoi Ana M, Platt Adam, Gilmer Tona M, Fu Xin-Yuan, Chin Y Eugene |date=August 2002 |title=Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activation |journal=J. Biol. Chem. |volume=277 |issue=34 |pages=30716–23 |publisher= |location = United States| issn = 0021-9258| pmid = 12070153 |doi = 10.1074/jbc.M202823200 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_2002-08-23_277_34/page/30716| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
*[[MCM5]]<ref name=pmid9843502>{{cite journal |last=Zhang |first=J J |authorlink= |coauthors=Zhao Y, Chait B T, Lathem W W, Ritzi M, Knippers R, Darnell J E |date=Dec 1998 |title=Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation |journal=EMBO J. |volume=17 |issue=23 |pages=6963–71 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 9843502 |doi = 10.1093/emboj/17.23.6963 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_embo-journal_1998-12-01_17_23/page/6962| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1171044 }}</ref><ref name=pmid11248027>{{cite journal |last=DaFonseca |first=C J |authorlink= |coauthors=Shu F, Zhang J J |date=March 2001 |title=Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=98 |issue=6 |pages=3034–9 |publisher= |location = United States| issn = 0027-8424| pmid = 11248027 |doi = 10.1073/pnas.061487598 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=30602 }}</ref>
*[[STAT2]]<ref name=pmid8621447>{{cite journal |last=Li |first=X |authorlink= |coauthors=Leung S, Qureshi S, Darnell J E, Stark G R |date=March 1996 |title=Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha |journal=J. Biol. Chem. |volume=271 |issue=10 |pages=5790–4 |publisher= |location = United States| issn = 0021-9258| pmid = 8621447 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_1996-03-08_271_10/page/5790| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.271.10.5790 }}</ref><ref name=pmid10446176>{{cite journal |last=Dumler |first=I |authorlink= |coauthors=Kopmann A, Wagner K, Mayboroda O A, Jerke U, Dietz R, Haller H, Gulba D C |date=August 1999 |title=Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells |journal=J. Biol. Chem. |volume=274 |issue=34 |pages=24059–65 |publisher= |location = United States| issn = 0021-9258| pmid = 10446176 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_1999-08-20_274_34/page/24058| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.274.34.24059 }}</ref><ref name=pmid12048190>{{cite journal |last=Fagerlund |first=Riku |authorlink= |coauthors=Mélen Krister, Kinnunen Leena, Julkunen Ilkka |date=August 2002 |title=Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5 |journal=J. Biol. Chem. |volume=277 |issue=33 |pages=30072–8 |publisher= |location = United States| issn = 0021-9258| pmid = 12048190 |doi = 10.1074/jbc.M202943200 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_2002-08-16_277_33/page/30072| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
*[[CD117]]<ref name=pmid9355737>{{cite journal |last=Deberry |first=C |authorlink= |coauthors=Mou S, Linnekin D |date=October 1997 |title=Stat1 associates with c-kit and is activated in response to stem cell factor |journal=Biochem. J. |volume=327 |issue= 1|pages=73–80 |publisher= |location = ENGLAND| issn = 0264-6021| pmid = 9355737 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1218765 }}</ref>
*[[Fanconi anemia, complementation group C]]<ref name=pmid10848598>{{cite journal |last=Pang |first=Q |authorlink= |coauthors=Fagerlie S, Christianson T A, Keeble W, Faulkner G, Diaz J, Rathbun R K, Bagby G C |date=July 2000 |title=The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors |journal=Mol. Cell. Biol. |volume=20 |issue=13 |pages=4724–35 |publisher= |location = United States| issn = 0270-7306| pmid = 10848598 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_molecular-and-cellular-biology_2000-07_20_13/page/4724| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1128/MCB.20.13.4724-4735.2000 |pmc=85895 }}</ref><ref name=pmid14499622>{{cite journal |last=Reuter |first=Tanja Y |authorlink= |coauthors=Medhurst Annette L, Waisfisz Quinten, Zhi Yu, Herterich Sabine, Hoehn Holger, Gross Hans J, Joenje Hans, Hoatlin Maureen E, Mathew Christopher G, Huber Pia A J |date=October 2003 |title=Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport |journal=Exp. Cell Res. |volume=289 |issue=2 |pages=211–21 |publisher= |location = United States| issn = 0014-4827| pmid = 14499622 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1016/S0014-4827(03)00261-1 }}</ref><ref name=pmid11520787>{{cite journal |last=Pang |first=Q |authorlink= |coauthors=Christianson T A, Keeble W, Diaz J, Faulkner G R, Reifsteck C, Olson S, Bagby G C |date=September 2001 |title=The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality |journal=Blood |volume=98 |issue=5 |pages=1392–401 |publisher= |location = United States| issn = 0006-4971| pmid = 11520787 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_blood_2001-09-01_98_5/page/1392| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1182/blood.V98.5.1392 }}</ref>
*{{le|CREB结合蛋白|CREB-binding protein}}<ref name=pmid8986769>{{cite journal |last=Zhang |first=J J |authorlink= |coauthors=Vinkemeier U, Gu W, Chakravarti D, Horvath C M, Darnell J E |date=Dec 1996 |title=Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=93 |issue=26 |pages=15092–6 |publisher= |location = United States| issn = 0027-8424| pmid = 8986769 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1073/pnas.93.26.15092 |pmc=26361 }}</ref>
*{{le|白介素27受体α亚基|Interleukin 27 receptor, alpha subunit}}<ref name=pmid12734330>{{cite journal |last=Takeda |first=Atsunobu |authorlink= |coauthors=Hamano Shinjiro, Yamanaka Atsushi, Hanada Toshikatsu, Ishibashi Tatsuro, Mak Tak W, Yoshimura Akihiko, Yoshida Hiroki |date=May 2003 |title=Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment |journal=J. Immunol. |volume=170 |issue=10 |pages=4886–90 |publisher= |location = United States| issn = 0022-1767| pmid = 12734330 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-immunology_2003-05-15_170_10/page/4886| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
*[[PIAS1]]<ref name=pmid10805787>{{cite journal |last=Liao |first=J |authorlink= |coauthors=Fu Y, Shuai K |date=May 2000 |title=Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=97 |issue=10 |pages=5267–72 |publisher= |location = United States| issn = 0027-8424| pmid = 10805787 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1073/pnas.97.10.5267 |pmc=25817 }}</ref>
*[[BRCA1]]<ref name=pmid10792030>{{cite journal |last=Ouchi |first=T |authorlink= |coauthors=Lee S W, Ouchi M, Aaronson S A, Horvath C M |date=May 2000 |title=Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=97 |issue=10 |pages=5208–13 |publisher= |location = United States| issn = 0027-8424| pmid = 10792030 |doi = 10.1073/pnas.080469697 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=25807 }}</ref>
*[[表皮生长因子受体]]<ref name=pmid10358079/><ref name=pmid12070153/>
*[[PTK2]]<ref name=pmid11278462>{{cite journal |last=Xie |first=B |authorlink= |coauthors=Zhao J, Kitagawa M, Durbin J, Madri J A, Guan J L, Fu X Y |date=June 2001 |title=Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion |journal=J. Biol. Chem. |volume=276 |issue=22 |pages=19512–23 |publisher= |location = United States| issn = 0021-9258| pmid = 11278462 |doi = 10.1074/jbc.M009063200 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_2001-06-01_276_22/page/19512| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
*[[Mammalian target of rapamycin]]<ref name=pmid12807916>{{cite journal |last=Kristof |first=Arnold S |authorlink= |coauthors=Marks-Konczalik Joanna, Billings Eric, Moss Joel |date=September 2003 |title=Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin |journal=J. Biol. Chem. |volume=278 |issue=36 |pages=33637–44 |publisher= |location = United States| issn = 0021-9258| pmid = 12807916 |doi = 10.1074/jbc.M301053200 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_2003-09-05_278_36/page/33636| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
*[[IFNAR2]]<ref name=pmid9121453>{{cite journal |last=Li |first=X |authorlink= |coauthors=Leung S, Kerr I M, Stark G R |date=April 1997 |title=Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling |journal=Mol. Cell. Biol. |volume=17 |issue=4 |pages=2048–56 |publisher= |location = United States| issn = 0270-7306| pmid = 9121453 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_molecular-and-cellular-biology_1997-04_17_4/page/2048| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=232052 }}</ref><ref name=pmid11301323>{{cite journal |last=Usacheva |first=A |authorlink= |coauthors=Smith R, Minshall R, Baida G, Seng S, Croze E, Colamonici O |date=June 2001 |title=The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor |journal=J. Biol. Chem. |volume=276 |issue=25 |pages=22948–53 |publisher= |location = United States| issn = 0021-9258| pmid = 11301323 |doi = 10.1074/jbc.M100087200 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-biological-chemistry_2001-06-22_276_25/page/22948| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
*[[PRKCD]]<ref name=pmid12807916/>
*[[TRADD]]<ref name=pmid10848577>{{cite journal |last=Wang |first=Y |authorlink= |coauthors=Wu T R, Cai S, Welte T, Chin Y E |date=July 2000 |title=Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation |journal=Mol. Cell. Biol. |volume=20 |issue=13 |pages=4505–12 |publisher= |location = United States| issn = 0270-7306| pmid = 10848577 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_molecular-and-cellular-biology_2000-07_20_13/page/4505| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1128/MCB.20.13.4505-4512.2000 |pmc=85828 }}</ref>
*[[C-jun]]<ref name=pmid10490649>{{cite journal |last=Zhang |first=X |authorlink= |coauthors=Wrzeszczynska M H, Horvath C M, Darnell J E |date=October 1999 |title=Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation |journal=Mol. Cell. Biol. |volume=19 |issue=10 |pages=7138–46 |publisher= |location = United States| issn = 0270-7306| pmid = 10490649 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_molecular-and-cellular-biology_1999-10_19_10/page/7138| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=84707 }}</ref>
*[[Calcitriol receptor]]<ref name=pmid11909970>{{cite journal |last=Vidal |first=Marcos |authorlink= |coauthors=Ramana Chilakamarti V, Dusso Adriana S |date=April 2002 |title=Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription |journal=Mol. Cell. Biol. |volume=22 |issue=8 |pages=2777–87 |publisher= |location = United States| issn = 0270-7306| pmid = 11909970 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_molecular-and-cellular-biology_2002-04_22_8/page/2777| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1128/MCB.22.8.2777-2787.2002 |pmc=133712 }}</ref>
*[[ISGF3G]]<ref name=pmid8943351>{{cite journal |last=Horvath |first=C M |authorlink= |coauthors=Stark G R, Kerr I M, Darnell J E |date=Dec 1996 |title=Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex |journal=Mol. Cell. Biol. |volume=16 |issue=12 |pages=6957–64 |publisher= |location = United States| issn = 0270-7306| pmid = 8943351 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_molecular-and-cellular-biology_1996-12_16_12/page/6957| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=231699 }}</ref>
*[[GNB2L1]]<ref name=pmid11301323/><ref name=pmid12960323>{{cite journal |last=Usacheva |first=Anna |authorlink= |coauthors=Tian Xinyong, Sandoval Raudel, Salvi Debra, Levy David, Colamonici Oscar R |date=September 2003 |title=The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex |journal=J. Immunol. |volume=171 |issue=6 |pages=2989–94 |publisher= |location = United States| issn = 0022-1767| pmid = 12960323 | bibcode = | oclc =| id = | url =https://archive.org/details/sim_journal-of-immunology_2003-09-15_171_6/page/2988| language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>

{{Div col end}}
==参考文献==
{{Reflist}}

==延伸阅读==
{{Refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Cebulla CM, Miller DM, Sedmak DD |title=Viral inhibition of interferon signal transduction |journal=Intervirology |volume=42 |issue= 5–6 |pages= 325–30 |year= 2000 |pmid= 10702714 |doi=10.1159/000053968 }}
*{{cite journal | author=Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW |title=Signaling through the JAK/STAT pathway, recent advances and future challenges |journal=Gene |volume=285 |issue= 1–2 |pages= 1–24 |year= 2002 |pmid= 12039028 |doi=10.1016/S0378-1119(02)00398-0 }}
*{{cite journal | author=Joseph AM, Kumar M, Mitra D |title=Nef: "necessary and enforcing factor" in HIV infection |journal=Curr. HIV Res. |volume=3 |issue= 1 |pages= 87–94 |year= 2005 |pmid= 15638726 |doi=10.2174/1570162052773013 }}
}}
{{Refend}}

==外部链接==
* {{FactorBook|STAT1}}
{{PDB Gallery|geneid=6772}}

{{Transcription factors|g4}}
{{JAK-STAT信号通路}}


{{PBB_Controls
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| update_protein_box = yes
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[[Category:转录因子]]
[[Category:信号转导]]

STAT1 - 版本历史

imported>InternetArchiveBot：​Add 15 books for verifiability (20251017sim)) #IABot (v2.0.9.5) (GreenC bot

imported>InternetArchiveBot：Add 15 books for verifiability (20251017sim)) #IABot (v2.0.9.5) (GreenC bot