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SCH-5472 - 版本历史
2026-07-19T20:25:00Z
本wiki上该页面的版本历史
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imported>Htmlzycq：使用HotCat已添加Category:二苯甲基化合物
2024-06-06T10:15:50Z
<p>使用<a href="/index.php?title=WP:HOTCAT&action=edit&redlink=1" class="new" title="WP:HOTCAT（页面不存在）">HotCat</a>已添加<a href="/wiki/Category:%E4%BA%8C%E8%8B%AF%E7%94%B2%E5%9F%BA%E5%8C%96%E5%90%88%E7%89%A9" title="Category:二苯甲基化合物">Category:二苯甲基化合物</a></p>
<p><b>新页面</b></p><div>{{Drugbox<br />
| Verifiedfields = changed<br />
| Watchedfields = changed<br />
| verifiedrevid = 451224999<br />
| IUPAC_name = 2-benzhydryl-1-methyl-piperidin-3-ol<br />
| image = SCH-5472.svg<br />
<br />
<!--Clinical data--><br />
| tradename = <br />
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --><br />
| pregnancy_US = <!-- A / B / C / D / X --><br />
| pregnancy_category = <br />
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --><br />
| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --><br />
| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --><br />
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --><br />
| legal_status =<br />
<br />
<!--Pharmacokinetic data--><br />
| bioavailability = <br />
| protein_bound = <br />
| metabolism = <br />
| elimination_half-life = <br />
| excretion =<br />
<br />
<!--Identifiers--><br />
| CAS_supplemental = (phenylsuccinate)<br />
| CAS_number_Ref = {{cascite|correct|CAS}}<br />
| CAS_number = 20068-90-0<br />
| UNII_Ref = {{fdacite|correct|FDA}}<br />
| UNII = 2D4V6AWP8N<br />
| ATC_prefix = <br />
| ATC_suffix = <br />
| PubChem = 209634<br />
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}<br />
| DrugBank = <br />
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}<br />
| ChemSpiderID = 181634<br />
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}<br />
| StdInChI = 1S/C19H23NO/c1-20-14-8-13-17(21)19(20)18(15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17-19,21H,8,13-14H2,1H3<br />
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}<br />
| StdInChIKey = DQNBDZSLMWHFTB-UHFFFAOYSA-N<br />
<br />
<!--Chemical data--><br />
| C=19 | H=23 | N=1 | O=1 <br />
| smiles = OC(CCCN1C)C1C(C2=CC=CC=C2)C3=CC=CC=C3<br />
}}<br />
'''{{PAGENAME}}'''是一种含氮[[有机化合物]]，分子式[[C19H23NO|C<sub>19</sub>H<sub>23</sub>NO]]，能作为[[兴奋剂]]<ref>{{cite journal | vauthors = Nodine JH, Bodi T, Slap J, Levy HA, Siegler PE | title = Preliminary trial of a new stimulant SCH 5472 in ambulatory patients with depression, exhaustion, or hypersomnia syndrome | journal = Antibiotic Medicine & Clinical Therapy | volume = 7 | pages = 771–6 | date = December 1960 | pmid = 13729397 }}</ref>，1950年代由[[先灵葆雅]]开发<ref name = "US2997478">{{ cite patent | country = US | status = patent | number = 2997478 | inventor = Walter LA, Sperber N | gdate = 1961-08-22 | assign1 = Schering | title = Oxygenated Piperidines and Process for their Manufacture }}</ref>。<br />
<br />
[[File:SCH-5472 synthesis.svg|thumb|center|500px|合成方式<ref>Walter, L., Springer, C., Kenney, J., Galen, S., & Sperber, N. (1968). Derivatives of 3-Piperidinol as Central Stimulants. Journal of Medicinal Chemistry, 11(4), 792–796. https://doi.org/10.1021/jm00310a612</ref>]]<br />
<br />
==参考文献==<br />
{{reflist}}<br />
<br />
[[Category:兴奋剂]]<br />
[[Category:2-苄基哌啶]]<br />
[[Category:二苯甲基化合物]]</div>
imported>Htmlzycq