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PD 144418 - 版本历史
2026-07-17T22:37:30Z
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| IUPAC_name = 1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine<br />
| image = PD144418.png<br />
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<!--Clinical data--><br />
| tradename = <br />
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --><br />
| pregnancy_US = <!-- A / B / C / D / X --><br />
| pregnancy_category = <br />
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --><br />
| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --><br />
| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --><br />
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --><br />
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<!--Pharmacokinetic data--><br />
| bioavailability = <br />
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<!--Identifiers--><br />
| CAS_number_Ref = {{cascite|correct|CAS}}<br />
| CAS_number = 154130-99-1<br />
| ATC_prefix = <br />
| ATC_suffix = <br />
| PubChem = <br />
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| DrugBank = <br />
| ChemSpiderID_Ref =<br />
| ChemSpiderID = 7992981<br />
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<!--Chemical data--><br />
| C=18 | H=22 | N=2 | O=1<br />
| smiles = CCCN1CCC=C(C1)C2=CC(=NO2)C3=CC=C(C=C3)C<br />
| StdInChI = 1S/C18H22N2O/c1-3-10-20-11-4-5-16(13-20)18-12-17(19-21-18)15-8-6-14(2)7-9-15/h5-9,12H,3-4,10-11,13H2,1-2H3<br />
| StdInChIKey = FOQRKFCLRMMKAT-UHFFFAOYSA-N<br />
}}<br />
'''{{PAGENAME}}'''（'''1,2,3,6-四氢-5-[3-(4-甲基苯基)-5-异𫫇唑基]-1-丙基-吡啶'''，{{langx|en|1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine}}）是一种[[有机化合物]]，化学式为[[C18H22N2O|C<sub>18</sub>H<sub>22</sub>N<sub>2</sub>O]]，可作为[[σ受体]]的选择性[[激动剂]]<ref name="Akunne_1997">{{cite journal |vauthors=Akunne HC, Whetzel SZ, Wiley JN, Corbin AE, Ninteman FW, Tecle H, Pei Y, Pugsley TA, Heffner TG | title = The pharmacology of the novel and selective sigma ligand, PD 144418 |url=https://archive.org/details/sim_neuropharmacology_1997-01_36_1/page/51 | journal = Neuropharmacology | volume = 36 | issue = 1 | pages = 51–62 |date=January 1997 | pmid = 9144641 | doi = 10.1016/S0028-3908(96)00161-X | s2cid = 1356055 }}</ref>。<br />
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==参考文献==<br />
{{reflist}}<br />
<br />
[[Category:Σ激动剂]]<br />
[[Category:对甲苯基化合物]]<br />
[[Category:异𫫇唑]]</div>
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