imported>Yubau：補充 PubChem CID 71604304（依英文條目及 PubChem 資料）

2026-04-19T01:07:49Z

補充 PubChem CID 71604304（依英文條目及 PubChem 資料）

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{{Drugbox
| Verifiedfields =
| verifiedrevid =
| IUPAC_name = 1-Pentyl-1''H''-indole-3-carboxylic acid 8-quinolinyl ester
| image = PB-22.png
| width = 200


| tradename =
| pregnancy_AU = 
| pregnancy_US = 
| pregnancy_category =
| legal_AU = 
| legal_CA = Schedule II
| legal_UK = Class B
| legal_US = Schedule I
| legal_DE = Anlage II
| routes_of_administration =


| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =


| CAS_number_Ref =
| CAS_number = 1400742-17-7
| ATC_prefix =
| ATC_suffix =
| PubChem =71604304
| DrugBank_Ref =
| DrugBank =
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = QM6J8F29FE
| ChemSpiderID = 29339966
| smiles = CCCCCN1C=C(C2=CC=CC=C21)C(=O)OC3=CC=CC4=C3N=CC=C4
| StdInChI = 1S/C23H22N2O2/c1-2-3-6-15-25-16-19(18-11-4-5-12-20(18)25)23(26)27-21-13-7-9-17-10-8-14-24-22(17)21/h4-5,7-14,16H,2-3,6,15H2,1H3
| StdInChIKey = ZAVGICCEAOUWFM-UHFFFAOYSA-N


| C=23 | H=22 | N=2 | O=2
}}

'''PB-22'''是一种[[狡詐家藥物]]，化学式为[[C23H22N2O2|C23H22N2O2]]，它在网络上作为大麻模拟剂供应，并在2013年于日本的合成大麻产品被发现。<ref>{{cite journal | vauthors = Uchiyama N, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y | title = Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products | doi = 10.1007/s11419-013-0182-9 | journal = Forensic Toxicology | year = 2013 | volume=31 | issue = 2 | pages=223–240| s2cid = 1279637 }}</ref><ref>{{cite journal | vauthors = Lin M, Ellis B, Eubanks LM, Janda KD | title = Pharmacokinetic Approach to Combat the Synthetic Cannabinoid PB-22 | journal = ACS Chemical Neuroscience | volume = 12 | issue = 14 | pages = 2573–2579 | date = July 2021 | pmid = 34254505 | doi = 10.1021/acschemneuro.1c00360 | s2cid = 235808519 }}</ref>PB-22在其吲哚环的3号位有酯基，可以被视作一类具有独特结构的合成大麻素。它在2014年于新西兰<ref>{{cite web |url=http://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=11247774 |title=Legal highs pulled from shelves |work=New Zealand Herald |vauthors=Jones N |date=1 May 2014 |publisher=New Zealand Media and Entertainment |access-date=18 August 2020 |archive-date=2017-12-01 |archive-url=https://web.archive.org/web/20171201081711/http://www.nzherald.co.nz/nz/news/article.cfm?c_id=1&objectid=11247774 |dead-url=no }}</ref>、同年于美国管控。<ref name=pmid24876364>{{cite journal | vauthors = Behonick G, Shanks KG, Firchau DJ, Mathur G, Lynch CF, Nashelsky M, Jaskierny DJ, Meroueh C | display-authors = 6 | title = Four postmortem case reports with quantitative detection of the synthetic cannabinoid, 5F-PB-22 | journal = Journal of Analytical Toxicology | volume = 38 | issue = 8 | pages = 559–562 | date = October 2014 | pmid = 24876364 | pmc = 4334789 | doi = 10.1093/jat/bku048 }}</ref><ref>{{cite web | url= http://www.deadiversion.usdoj.gov/drug_chem_info/spice/pb22.pdf | title= PB-22 and 5F-PB-22 | publisher= [[美国缉毒局|DEA]], Office of Diversion Control | access-date= 2023-11-24 | archive-date= 2024-05-21 | archive-url= https://web.archive.org/web/20240521111109/https://www.deadiversion.usdoj.gov/drug_chem_info/spice/pb22.pdf | dead-url= no }}</ref>

== 参考文献 ==
{{reflist}}

{{大麻素}}

[[Category:大麻素]]
[[Category:策划药]]
[[Category:吲哚]]
[[Category:正戊基化合物]]

PB-22 - 版本历史

imported>Yubau：​補充 PubChem CID 71604304（依英文條目及 PubChem 資料）

imported>Yubau：補充 PubChem CID 71604304（依英文條目及 PubChem 資料）