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ORG-25935 - 版本历史
2026-07-18T17:47:44Z
本wiki上该页面的版本历史
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imported>Htmlzycq：使用HotCat已添加Category:羧酸
2025-02-15T10:59:05Z
<p>使用<a href="/index.php?title=WP:HOTCAT&action=edit&redlink=1" class="new" title="WP:HOTCAT（页面不存在）">HotCat</a>已添加<a href="/wiki/Category:%E7%BE%A7%E9%85%B8" title="Category:羧酸">Category:羧酸</a></p>
<p><b>新页面</b></p><div>{{Drugbox<br />
| verifiedrevid = <br />
| IUPAC_name = 2-([(1''R'',2''S'')-6-Methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl]methyl-methylamino)acetic acid<br />
| image =Org 25935.svg<br />
| width = 230<br />
<br />
<!--Clinical data--><br />
| tradename = <br />
| legal_status =<br />
<br />
<!--Pharmacokinetic data--><br />
| bioavailability = <br />
| metabolism = <br />
| elimination_half-life = <br />
| excretion =<br />
<br />
<!--Identifiers--><br />
| index2_label = HCl<br />
| CAS_number_Ref = {{cascite|correct|CAS}}<br />
| CAS_number = 1147011-84-4<br />
| CAS_number2_Ref = {{cascite|correct|CAS}}<br />
| CAS_number2 = 949588-40-3<br />
| CAS_supplemental = <br />
| UNII_Ref = {{fdacite|correct|FDA}}<br />
| UNII = 55L20667O4<br />
| UNII2_Ref = {{fdacite|correct|FDA}}<br />
| UNII2 = H6MSM69SSM<br />
| PubChem = 11717074<br />
| ChemSpiderID = 9891795<br />
<br />
<!--Chemical data--><br />
| C = 21 | H = 25 | N = 1 | O = 3 <br />
| smiles = O=C(O)CN(C)C[C@@H]2[C@@H](c1c(cc(OC)cc1)CC2)c3ccccc3<br />
| StdInChI = 1S/C21H25NO3/c1-22(14-20(23)24)13-17-9-8-16-12-18(25-2)10-11-19(16)21(17)15-6-4-3-5-7-15/h3-7,10-12,17,21H,8-9,13-14H2,1-2H3,(H,23,24)/t17-,21+/m1/s1<br />
| StdInChIKey = UEBBYLJZCHTLEG-UTKZUKDTSA-N<br />
}}<br />
'''{{PAGENAME}}'''或称为'''SCH-900435'''是一种含氮[[有机化合物]]，化学式[[C21H25NO3|{{chem2|C21H25NO3}}]]，由美国[[欧加农]]（Organon & Co.）制药公司研发，可作为[[甘氨酸转运蛋白]][[GlyT-1]]的选择性抑制剂<ref>{{cite journal | vauthors = Molander A, Lidö HH, Löf E, Ericson M, Söderpalm B | title = The glycine reuptake inhibitor Org 25935 decreases ethanol intake and preference in male wistar rats | journal = Alcohol and Alcoholism | volume = 42 | issue = 1 | pages = 11–8 | pmid = 17098748 | doi = 10.1093/alcalc/agl085 | year = 2006 | doi-access = free }}</ref>。<br />
<br />
==参考文献==<br />
{{reflist}}<br />
<br />
[[Category:作用于神经系统的药物]]<br />
[[Category:苯基化合物]]<br />
[[Category:羧酸]]</div>
imported>Htmlzycq