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JWH-019 - 版本历史
2026-07-19T02:31:34Z
本wiki上该页面的版本历史
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2025-11-27T15:52:11Z
<p><span class="autocomment">top：</span> bot:<a href="/index.php?title=User:Zestbot/Bot17&action=edit&redlink=1" class="new" title="User:Zestbot/Bot17（页面不存在）">替換lang-x模板為langx</a></p>
<p><b>新页面</b></p><div>{{Drugbox<br />
| verifiedrevid = 451563324<br />
| IUPAC_name = 1-Hexyl-3-(naphthalen-1-oyl)indole<br />
| image = JWH019.svg<br />
| image_class = skin-invert-image<br />
<br />
<!--Clinical data--><br />
| tradename = <br />
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --><br />
| pregnancy_US = <!-- A / B / C / D / X --><br />
| pregnancy_category = <br />
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --><br />
| legal_CA = Schedule II<br />
| legal_US = Schedule I<br />
| legal_DE = Anlage II<br />
| legal_UK = Class B<br />
| legal_status = Illegal in Sweden, I-N (Poland)<ref name="isap.sejm">{{cite web | title = Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii ( Dz.U. 2011 nr 105 poz. 614 ) | url = http://isap.sejm.gov.pl/DetailsServlet?id=WDU20111050614 | publisher = Internetowy System Aktów Prawnych | access-date = 12 June 2011}}</ref><br />
| routes_of_administration =<br />
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<!--Pharmacokinetic data--><br />
| bioavailability = <br />
| protein_bound = <br />
| metabolism = <br />
| elimination_half-life = <br />
| excretion =<br />
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<!--Identifiers--><br />
| CAS_number_Ref = {{cascite|correct|??}}<br />
| CAS_number = 209414-08-4<br />
| UNII_Ref = {{fdacite|correct|FDA}}<br />
| UNII = 0Z73828O4J<br />
| ATC_prefix = <br />
| ATC_suffix = <br />
| PubChem = <br />
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}<br />
| DrugBank = <br />
| ChemSpiderID = 24598813<br />
<br />
<!--Chemical data--><br />
| C=25 | H=25 | N=1 | O=1 <br />
| smiles = c3cccc2c3cccc2C(=O)c1cn(CCCCCC)c4c1cccc4<br />
| StdInChI = 1S/C25H25NO/c1-2-3-4-9-17-26-18-23(21-14-7-8-16-24(21)26)25(27)22-15-10-12-19-11-5-6-13-20(19)22/h5-8,10-16,18H,2-4,9,17H2,1H3<br />
| StdInChIKey = PALJPGHWDUHUPO-UHFFFAOYSA-N<br />
}}<br />
'''{{PAGENAMEBASE}}'''，化学名'''1-己基-3-(1-萘甲酰基)吲哚'''（{{langx|en|1-hexyl-3-(1-naphthoyl)indole}}），分子式[[C25H25NO|{{chem2|C25H25NO}}]]，属于[[萘甲酰基吲哚]]类[[JWH大麻素列表|JWH系列大麻素]]，可作为[[镇痛药]]<ref name="pmid10940540">{{cite journal | vauthors = Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, Showalter VM, Abood ME, Martin BR | display-authors = 6 | title = Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding | url = https://archive.org/details/sim_drug-and-alcohol-dependence_2000-08-01_60_2/page/132 | journal = Drug and Alcohol Dependence | volume = 60 | issue = 2 | pages = 133–40 | date = August 2000 | pmid = 10940540 | doi = 10.1016/S0376-8716(99)00152-0 }}</ref><ref name="pmid17982473">{{cite journal | vauthors = Poso A, Huffman JW | title = Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands | journal = British Journal of Pharmacology | volume = 153 | issue = 2 | pages = 335–46 | date = January 2008 | pmid = 17982473 | pmc = 2219524 | doi = 10.1038/sj.bjp.0707567 }}</ref><ref name="pmid18537620">{{cite journal | vauthors = Ashton JC, Wright JL, McPartland JM, Tyndall JD | title = Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists | journal = Current Medicinal Chemistry | volume = 15 | issue = 14 | pages = 1428–43 | year = 2008 | pmid = 18537620 | doi = 10.2174/092986708784567716 }}</ref>。<br />
<br />
==参考文献==<br />
{{reflist}}<br />
<br />
[[Category:JWH大麻素]]<br />
[[Category:萘甲酰基吲哚]]<br />
[[Category:策划药]]<br />
[[Category:CB1受体激动剂]]<br />
[[Category:CB2受体激动剂]]<br />
[[Category:正己基化合物]]</div>
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