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IL4R - 版本历史
2026-07-14T15:58:57Z
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2025-02-08T02:29:30Z
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<p><b>新页面</b></p><div>{{Infobox_gene}}<br />
{{Infobox protein family<br />
| Symbol = IL4Ra_N<br />
| Name = Interleukin-4 receptor alpha chain, N-terminal<br />
| image = PDB 1iar EBI.jpg<br />
| width = <br />
| caption = interleukin-4 / receptor alpha chain complex<br />
| Pfam = PF09238<br />
| Pfam_clan = <br />
| InterPro = IPR015319<br />
| SMART = <br />
| PROSITE = <br />
| MEROPS = <br />
| SCOP = 1iar<br />
| TCDB = <br />
| OPM family = <br />
| OPM protein = <br />
| CAZy = <br />
| CDD = <br />
}}<br />
'''白介素-4受体α亚基'''（Interleukin-4 receptor subunit alpha，缩写'''IL4R-α'''或'''IL4R'''）也称为'''分化簇124'''（'''CD124'''，cluster of differentiation 124）是一种细胞表面蛋白质，由人类基因 ''{{PAGENAME}}'' 编码<ref name="entrez">{{cite web| title = Entrez Gene: IL4R interleukin 4 receptor| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3566| access-date = 2024-12-30| archive-date = 2010-03-07| archive-url = https://web.archive.org/web/20100307152635/http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3566| dead-url = no}}</ref>，与[[CD132|γ链]]（CD132）共同组成I型[[白介素-4受体]]（IL4R type I），或与[[IL13RA1|白介素-13受体α1]]（CD213a1）组成II型白介素-4受体（IL4R type II），除了结合能[[白细胞介素-4|白介素-4]]还能结合[[白细胞介素-13|白介素-13]]（IL13）<ref>{{cite journal | vauthors = McCormick SM, Heller NM | title = Commentary: IL-4 and IL-13 receptors and signaling | journal = Cytokine | volume = 75 | issue = 1 | pages = 38–50 | date = September 2015 | pmid = 26187331 | pmc = 4546937 | doi = 10.1016/j.cyto.2015.05.023 }}</ref>。<br />
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== 参考资料 ==<br />
{{Reflist}}<br />
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== 外部链接 ==<br />
* {{MeshName|CD124+Antigen}}<br />
* [https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/P24394 PDBe-KB] {{Wayback|url=https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/P24394 |date=20250123101511 }} provides an overview of all the structure information available in the PDB for Human Interleukin-4 receptor subunit alpha<br />
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{{细胞因子受体}}<br />
{{分化簇}}<br />
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[[Category:分化群]]</div>
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