https://arolstar52-zhtest.hf.space/index.php?action=history&feed=atom&title=HEPES
HEPES - 版本历史
2026-07-15T19:01:53Z
在这个wiki上该页的修订历史
MediaWiki 1.43.9
https://arolstar52-zhtest.hf.space/index.php?title=HEPES&diff=4508385&oldid=prev
imported>Nucleus hydro elemon：Cat-a-lot：分类间复制：从Category:乙醇胺到Category:羟乙基化合物
2025-08-28T09:24:10Z
<p><a href="/wiki/Help:Cat-a-lot" class="mw-redirect" title="Help:Cat-a-lot">Cat-a-lot</a>：分类间复制：从<a href="/wiki/Category:%E4%B9%99%E9%86%87%E8%83%BA" title="Category:乙醇胺">Category:乙醇胺</a>到<a href="/wiki/Category:%E7%BE%9F%E4%B9%99%E5%9F%BA%E5%8C%96%E5%90%88%E7%89%A9" title="Category:羟乙基化合物">Category:羟乙基化合物</a></p>
<p><b>新页面</b></p><div>{{chembox<br />
| Verifiedfields = changed<br />
| Watchedfields = changed<br />
| verifiedrevid = 448969371<br />
| Name = HEPES<br />
| ImageFile = HEPES.png<br />
| ImageName = chemical structure of HEPES<br />
| PIN = 2-[4-(2-Hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid<br />
| OtherNames = HEPES<br />
|Section1={{Chembox Identifiers<br />
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}<br />
| ChemSpiderID = 22278<br />
| UNII_Ref = {{fdacite|correct|FDA}}<br />
| UNII = RWW266YE9I<br />
| InChI = 1/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)<br />
| InChIKey = JKMHFZQWWAIEOD-UHFFFAOYAC<br />
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}<br />
| StdInChI = 1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)<br />
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}<br />
| StdInChIKey = JKMHFZQWWAIEOD-UHFFFAOYSA-N<br />
| CASNo_Ref = {{cascite|correct|CAS}}<br />
| CASNo = 7365-45-9<br />
| RTECS = TL6809000<br />
| EINECS = 230-907-9<br />
| Beilstein = 883043<br />
| ChEBI_Ref = {{ebicite|correct|EBI}}<br />
| ChEBI = 42334<br />
| SMILES = OCCN1CC[NH+](CCS(=O)([O-])=O)CC1<br />
| PubChem = 23831<br />
}}<br />
|Section2={{Chembox Properties<br />
| C=8 | H=18 | N=2 | O=4 | S=1<br />
| MolarMass = 238.3012 g/mol<br />
| Appearance = white crystalline powder<br />
| Density = Not applicable<br />
| Solubility = 40 g/100 ml (20°C)<br />
| MeltingPt = >234-238°C (453-457K)<br />
| pKa = 3 (p''K''<sub>a1</sub>),<br> 7.5 (p''K''<sub>a2</sub>)<ref>{{cite journal |vauthors = Johnson MA, Seifert S, Petrache HI, Kimble-Hill AC |date= 2014|title= Phase Coexistence in Single-Lipid Membranes Induced by Buffering Agents|journal= Langmuir|volume= 30|issue= 33|pages= 9880-9885|doi= 10.1021/la5018938 |pmc=4148158|access-date=}}</ref><br />
}}<br />
|Section7={{Chembox Hazards<br />
| ExternalSDS = [https://www.sigmaaldrich.com/US/en/product/sigma/h3375]<br />
| MainHazards = Eye Irritant<br />
| NFPA-H = 1<br />
| NFPA-F = 0<br />
| NFPA-R = 1<br />
| FlashPt = Non-flammable<br />
| GHSPictograms = {{GHS07}}<br />
| GHSSignalWord = 警告<br />
| HPhrases = {{H-phrases|315|319|335}}<br />
| PPhrases = {{P-phrases|261|264|270|271|280|301+312|302+352|304+312|304+340|305+351+338|312|321|322|330|332+313|337+313|362|363|403+233|405|501}}<br />
}}<br />
}}<br />
<br />
'''HEPES'''（'''4-(2-羟乙基)-1-哌嗪乙磺酸'''）是一种两性离子磺酸[[缓冲溶液|缓冲剂]]，它是二十种{{le|古德缓冲试剂|Good's buffers}}之一，广泛用于[[细胞培养]]。<ref>{{cite journal |vauthors=Baicu SC, Taylor MJ | title=Acid-base buffering in organ preservation solutions as a function of temperature: new parameters for comparing buffer capacity and efficiency | journal=Cryobiology | volume=45 | issue=1 | year=2002 | pages=33–48 | pmid=12445548 | doi=10.1016/S0011-2240(02)00104-9}}</ref>它和1-甲基-3-乙基咪唑𬭩形成[[离子液体]]。<ref>Mohamed Taha; et al. Good's buffers as a basis for developing self-buffering and biocompatible ionic liquids for biological research. Green Chem., 2014,16, 3149-3159. {{doi|10.1039/C4GC00328D}}.</ref><br />
<br />
==参考文献==<br />
{{reflist}}<br />
<br />
[[Category:伯醇]]<br />
[[Category:哌嗪]]<br />
[[Category:缓冲液]]<br />
[[Category:磺酸]]<br />
[[Category:乙醇胺]]<br />
[[Category:羟乙基化合物]]</div>
imported>Nucleus hydro elemon