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HA-966 - 版本历史
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2023年12月28日 (四) 00:59 imported>Innerstream
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<p></p>
<p><b>新页面</b></p><div>{{Drugbox<br />
| Watchedfields = <br />
| verifiedrevid = <br />
| IUPAC_name = 3-Amino-1-hydroxy-pyrrolidin-2-one<br />
| image = HA-966.svg<br />
| width = 200<br />
<br />
<!--Clinical data--><br />
| tradename = <br />
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --><br />
| pregnancy_US = <!-- A / B / C / D / X --><br />
| pregnancy_category = <br />
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 --><br />
| legal_CA = <!-- / Schedule I, II, III, IV, V, VI, VII, VIII --><br />
| legal_UK = <!-- GSL / P / POM / CD / Class A, B, C --><br />
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --><br />
| legal_status = <br />
| routes_of_administration =<br />
<br />
<!--Pharmacokinetic data--><br />
| bioavailability = <br />
| protein_bound = <br />
| metabolism = <br />
| elimination_half-life = <br />
| excretion =<br />
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<!--Identifiers--><br />
| CAS_number = 1003-51-6<br />
| CAS_number_Ref = {{cascite|correct|CAS}}<br />
| UNII_Ref = {{fdacite|correct|FDA}}<br />
| UNII = F2JLV9220T<br />
| ATC_prefix = <br />
| ATC_suffix = <br />
| PubChem = 1232<br />
| IUPHAR_ligand = <br />
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}<br />
| DrugBank = <br />
| ChemSpiderID = 1195<br />
| StdInChI = 1S/C4H8N2O2/c5-3-1-2-6(8)4(3)7/h3,8H,1-2,5H2<br />
| StdInChIKey = HCKUBNLZMKAEIN-UHFFFAOYSA-N<br />
<br />
<!--Chemical data--><br />
| C=4 | H=8 | N=2 | O=2 <br />
| smiles = O=C1C(CCN1O)N<br />
| solubility = 31.9 g/100 mL (25 °C)<ref>Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs). Retrieved from SciFinder. [2023-02-11].</ref><br />
}}<br />
'''{{PAGENAMEBASE}}'''（化学名'''(±) 3-氨基-1-羟基吡咯烷-2-酮'''，{{lang|en|(±) 3-Amino-1-hydroxy-pyrrolidin-2-one}}），分子式[[C4H8N2O2|C<sub>4</sub>H<sub>8</sub>N<sub>2</sub>O<sub>2</sub>]]，是一种用于科研的[[甘氨酸受体]]和[[N-甲基-D-天門冬胺酸受體]][[拮抗剂]]或[[效能 (药理学)|低效]][[部分激动剂]]<ref name="pmid1838797">{{cite journal |vauthors=Vartanian MG, Taylor CP |title=Different stereoselectivity of the enantiomers of HA-966 (3-amino-1-hydroxy-2-pyrrolidinone) for neuroprotective and anticonvulsant actions in vivo. |journal=Neuroscience Letters |volume=133 |issue=1 |pages=109–12 |date=Nov 1991 |pmid=1838797 |doi=10.1016/0304-3940(91)90069-6 |s2cid=36483282 }}</ref>。<br />
<br />
==参考文献==<br />
{{Reflist|2}}<br />
<br />
==外部链接==<br />
<br />
[[Category:伯胺]]<br />
[[Category:吡咯烷酮]]<br />
[[Category:N-甲基-D-天冬氨酸受体拮抗剂]]<br />
[[Category:羟胺]]</div>
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