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CYP305M2 - 版本历史
2026-07-16T04:50:21Z
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2020-04-28T22:46:16Z
<p><span class="autocomment">參考文獻</span></p>
<p><b>新页面</b></p><div>{{Infobox nonhuman protein<br />
| Name = <br />
| image = <br />
| width = <br />
| caption = <br />
| Organism =[[飛蝗]]<br />
<br />
| TaxID = 7004<br />
| Symbol = CYP305M2<br />
| AltSymbols = <br />
| ATC_prefix = <br />
| ATC_suffix = <br />
| ATC_supplemental = <br />
| CAS_number = <br />
| CAS_supplemental = <br />
| DrugBank = <br />
| EntrezGene = <br />
| HomoloGene = <br />
| PDB = <br />
| RefSeqmRNA = <br />
| RefSeqProtein = <br />
| UniProt = A0A410UD22<br />
| ECnumber = 1.14.-.-<br />
| Chromosome = <br />
| EntrezChromosome = <br />
| GenLoc_start = <br />
| GenLoc_end = <br />
}}<br />
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[[File:Locusta migratoria.jpg|thumb|散居型的蝗蟲不會釋放[[苯乙腈]]]]<br />
'''細胞色素P305M2'''（CYP305M2，舊稱LM16181）是[[飛蝗]]的一種[[細胞色素P450]]，於2019年由[[中國科學院]]的研究團隊發表，其[[胺基酸]]序列與其他昆蟲的細胞色素P305A（CYP305A）較為接近。CYP305M2可催化蝗蟲體內[[苯乙腈]][[生物合成]]的一個關鍵步驟，後者對[[鳥類]]等蝗蟲的天敵具[[警戒作用]]，並可在蝗蟲被攻擊時進一步轉換成具毒性的[[氰化氫]]<ref name="Wei_2019">{{cite journal | vauthors = Wei J, Shao W, Cao M, Ge J, Yang P, Chen L, Wang X, Kang L | title = Phenylacetonitrile in locusts facilitates an antipredator defense by acting as an olfactory aposematic signal and cyanide precursor | journal = Science Advances | volume = 5 | issue = 1 | pages = eaav5495 | date = January 2019 | pmid = 30746481 | pmc = 6357733 | doi = 10.1126/sciadv.aav5495 }}</ref><ref>{{cite web | title = Cytochrome P450 [Locusta migratoria] | url = https://www.ncbi.nlm.nih.gov/protein/1562184486 | work = NCBI Protein | publisher = National Center for Biotechnology Information, U.S. National Library of Medicine }}</ref>。[[蝗蟲]]有散居型（solitary）與聚居型（gregarious）兩種型態，其中只有聚居型的蝗蟲會表現CYP305M2基因並合成苯乙腈，CYP305M2廣泛分布於其組織中，尤以頭部和後肢的濃度較高；散居型的蝗蟲則闕如<ref name="Wei_2019"/>。<br />
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[[Image:Phenylacetonitrile biosynthesis.svg|thumb|left|500px|[[苯乙腈]][[生物合成]]的反應途徑]]<br />
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==參考文獻==<br />
{{Reflist}}<br />
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{{Cytochrome P450}}<br />
[[Category:EC 1.14]]<br />
[[Category:细胞色素P450|305]]</div>
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