https://arolstar52-zhtest.hf.space/index.php?action=history&feed=atom&title=CXCL9 2026-07-14T18:23:03Z 在这个wiki上该页的修订历史 MediaWiki 1.43.9 https://arolstar52-zhtest.hf.space/index.php?title=CXCL9&diff=230215&oldid=prev 2026-02-10T10:45:49Z

<p></p> <p><b>新页面</b></p><div>{{Infobox_gene}}<br /> &#039;&#039;&#039;CXCL9&#039;&#039;&#039;（{{langx|en|Chemokine (C-X-C motif) ligand 9}}）化学式为C&lt;sub&gt;509&lt;/sub&gt;H&lt;sub&gt;877&lt;/sub&gt;O&lt;sub&gt;148&lt;/sub&gt;N&lt;sub&gt;159&lt;/sub&gt;S&lt;sub&gt;4&lt;/sub&gt;&lt;ref&gt;{{Cite web |title=Expasy - ProtParam |url=https://web.expasy.org/cgi-bin/protparam/protparam_bis.cgi?Q07325@23-125@ |website=web.expasy.org |access-date=2026-02-10}}&lt;/ref&gt;是一小分子的[[细胞因子]]属于CXC[[趋化因子]]家族，又被称作“干扰素伽玛诱导的单核细胞因子”（Monokine induced by gamma interferon, MIG）&lt;ref name=liao&gt;Liao F, Rabin RL, Yannelli JR, Koniaris LG, Vanguri P, Farber JM. Human Mig chemokine: biochemical and functional characterization. J Exp Med. 1995 Nov 1;182(5):1301-14.&lt;/ref&gt;。CXCL9是[[T细胞]]趋化因子&lt;ref name=liao/&gt;。[[干扰素伽玛]]诱导CXCL9的表达。人类的CXCL9与[[CXCL10]]，[[CXCL11]]的基因相邻聚集在第四染色体上&lt;ref&gt;Lee HH, Farber JM. Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine &quot;mini-cluster&quot;. Cytogenet Cell Genet. 1996;74(4):255-8.&lt;/ref&gt;。CXCL9，CXCL10, CXCL11结合趋化因子受体[[CXCR3]]而起其细胞趋化作用&lt;ref&gt;Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, Clark-Lewis I, Baggiolini M, Moser B. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 1996 Sep 1;184(3):963-9.&lt;/ref&gt;&lt;ref&gt;Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS, DeMartino JA. Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors. J Biol Chem. 1998 Jul 17;273(29):18288-91.&lt;/ref&gt;。<br /> <br /> == 参见 ==<br /> *[[趋化因子]]<br /> *[[CXCR3]]<br /> *[[CXCL10]]<br /> *[[CXCL11]]<br /> <br /> == 参考文献 ==<br /> {{Reflist}}<br /> <br /> == 外部链接 ==<br /> *[http://content.nejm.org/cgi/content/extract/354/6/610 Charo IF, Ransohoff RM. The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med. 2006 Feb 9;354(6):610-21.]{{Wayback|url=http://content.nejm.org/cgi/content/extract/354/6/610 |date=20070110225703 }}<br /> <br /> {{细胞因子}}<br /> <br /> [[Category:细胞因子]]<br /> [[Category:免疫学]]</div>

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