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CEBPG - 版本历史
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'''CCAAT/增强子结合蛋白γ'''，简称'''C/EBP-γ'''或'''CEBPG'''是化学式为：C<sub>694</sub>H<sub>1162</sub>O<sub>231</sub>N<sub>222</sub>S<sub>3</sub><ref>{{Cite web |title=Expasy - ProtParam |url=https://web.expasy.org/cgi-bin/protparam/protparam_bis.cgi?P53567@1-150@ |website=web.expasy.org |access-date=2026-01-24}}</ref>，一种在人体中由''CEBPG''[[基因]]编码的[[蛋白质]]。<ref name="pmid1884998">{{cite journal |vauthors=Williams SC, Cantwell CA, Johnson PF |date=Oct 1991 |title=A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro |journal=Genes Dev |volume=5 |issue=9 |pages=1553–67 |doi=10.1101/gad.5.9.1553 |pmid=1884998 |doi-access=free}}</ref><ref name="entrez">{{cite web |title=Entrez Gene: CEBPG CCAAT/enhancer binding protein (C/EBP), gamma |url=https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1054 |access-date=2022-11-01 |archive-date=2009-05-11 |archive-url=https://web.archive.org/web/20090511065906/http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1054 |dead-url=no }}</ref><br />
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C/EBP转录因子家族调节病毒和细胞CCAAT/增强子元件介导的转录。C/EBP蛋白包含[[BZIP结构域|bZIP]]区域，其特征在于蛋白质的C端一半中的两个基序：一个参与[[DNA]]结合的碱性区域和一个参与二聚化的[[亮氨酸]]拉链基序。 C/EBP家族由几种相关的蛋白质组成，即[[CEBPA|C/EBP-α]]、[[CEBPB|C/EBP-β]]、'''C/EBP-γ'''和[[CEBPD|C/EBP-δ]]，它们形成同源[[二聚体]]并相互形成异源二聚体。CEBPG可以与Fos合作以结合PRE-I增强子元件。<ref name="entrez" /><br />
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== 参见 ==<br />
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* [[CCAAT/增强子结合蛋白]]<br />
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== 参考文献 ==<br />
{{reflist}}<br />
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== 阅读 ==<br />
{{refbegin|2}}<br />
*{{cite journal |vauthors=Nishizawa M, Nagata S |year=1992 |title=cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein. |url=https://archive.org/details/sim_febs-letters_1992-03-02_299_1/page/36 |journal=FEBS Lett. |volume=299 |issue=1 |pages=36–8 |doi=10.1016/0014-5793(92)80094-W |pmid=1371974 |s2cid=34097395 |doi-access=free}}<br />
*{{cite journal |display-authors=etal |vauthors=Thomassin H, Hamel D, Bernier D |year=1992 |title=Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma. |url=https://archive.org/details/sim_nucleic-acids-research_1992-06-25_20_12/page/3090 |journal=Nucleic Acids Res. |volume=20 |issue=12 |pages=3091–8 |doi=10.1093/nar/20.12.3091 |pmc=312443 |pmid=1377818}}<br />
*{{cite journal |vauthors=Nishizawa M, Wakabayashi-Ito N, Nagata S |year=1991 |title=Molecular cloning of cDNA and a chromosomal gene encoding GPE1-BP, a nuclear protein which binds to granulocyte colony-stimulating factor promoter element 1. |url=https://archive.org/details/sim_febs-letters_1991-04-22_282_1/page/94 |journal=FEBS Lett. |volume=282 |issue=1 |pages=95–7 |doi=10.1016/0014-5793(91)80452-9 |pmid=1709121 |s2cid=948618}}<br />
*{{cite journal |display-authors=etal |vauthors=Cooper C, Henderson A, Artandi S |year=1996 |title=Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activators. |journal=Nucleic Acids Res. |volume=23 |issue=21 |pages=4371–7 |doi=10.1093/nar/23.21.4371 |pmc=307392 |pmid=7501458}}<br />
*{{cite journal |vauthors=Davydov IV, Bohmann D, Krammer PH, Li-Weber M |year=1995 |title=Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter. |url=https://archive.org/details/sim_gene_1995_161_2/page/271 |journal=Gene |volume=161 |issue=2 |pages=271–5 |doi=10.1016/0378-1119(95)00271-7 |pmid=7665092}}<br />
*{{cite journal |display-authors=etal |vauthors=Lundgren M, Larsson C, Femino A |year=1994 |title=Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site. |url=https://archive.org/details/sim_journal-of-immunology_1994-10-01_153_7/page/2982 |journal=J. Immunol. |volume=153 |issue=7 |pages=2983–95 |pmid=8089482}}<br />
*{{cite journal |vauthors=Martin ML, Lieberman PM, Curran T |year=1996 |title=Fos-Jun dimerization promotes interaction of the basic region with TFIIE-34 and TFIIF. |url=https://archive.org/details/sim_molecular-and-cellular-biology_1996-05_16_5/page/2110 |journal=Mol. Cell. Biol. |volume=16 |issue=5 |pages=2110–8 |doi=10.1128/mcb.16.5.2110 |pmc=231198 |pmid=8628277}}<br />
*{{cite journal |vauthors=Gao H, Parkin S, Johnson PF, Schwartz RC |year=2002 |title=C/EBP gamma has a stimulatory role on the IL-6 and IL-8 promoters. |url=https://archive.org/details/sim_journal-of-biological-chemistry_2002-10-11_277_41/page/38826 |journal=J. Biol. Chem. |volume=277 |issue=41 |pages=38827–37 |doi=10.1074/jbc.M206224200 |pmid=12177065 |doi-access=free}}<br />
*{{cite journal |display-authors=etal |vauthors=Strausberg RL, Feingold EA, Grouse LH |year=2003 |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue=26 |pages=16899–903 |bibcode=2002PNAS...9916899M |doi=10.1073/pnas.242603899 |pmc=139241 |pmid=12477932 |doi-access=free}}<br />
*{{cite journal |display-authors=etal |vauthors=Hattori T, Ohoka N, Inoue Y |year=2003 |title=C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer. |journal=Oncogene |volume=22 |issue=9 |pages=1273–80 |doi=10.1038/sj.onc.1206204 |pmid=12618752 |doi-access=free}}<br />
*{{cite journal |vauthors=Newman JR, Keating AE |year=2003 |title=Comprehensive identification of human bZIP interactions with coiled-coil arrays. |url=https://archive.org/details/sim_science_2003-06-27_300_5628/page/2096 |journal=Science |volume=300 |issue=5628 |pages=2097–101 |bibcode=2003Sci...300.2097N |doi=10.1126/science.1084648 |pmid=12805554 |s2cid=36715183}}<br />
*{{cite journal |display-authors=etal |vauthors=Gerhard DS, Wagner L, Feingold EA |year=2004 |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue=10B |pages=2121–7 |doi=10.1101/gr.2596504 |pmc=528928 |pmid=15489334}}<br />
*{{cite journal |display-authors=etal |vauthors=Rual JF, Venkatesan K, Hao T |year=2005 |title=Towards a proteome-scale map of the human protein-protein interaction network. |url=https://archive.org/details/sim_nature-uk_2005-10-20_437_7062/page/1172 |journal=Nature |volume=437 |issue=7062 |pages=1173–8 |bibcode=2005Natur.437.1173R |doi=10.1038/nature04209 |pmid=16189514 |s2cid=4427026}}<br />
*{{cite journal |display-authors=etal |vauthors=Mullins DN, Crawford EL, Khuder SA |year=2006 |title=CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma. |journal=BMC Cancer |volume=5 |pages=141 |doi=10.1186/1471-2407-5-141 |pmc=1310620 |pmid=16255782}}<br />
{{refend}}<br />
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== 外部链接 ==<br />
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* {{MeshName|CEBPG+protein,+human}}<br />
* {{UCSC gene info|CEBPG}}<br />
{{转录因子与细胞内受体|g1}}</div>
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