https://arolstar52-zhtest.hf.space/index.php?action=history&feed=atom&title=CD33CD33 - 版本历史2026-07-05T17:00:37Z在这个wiki上该页的修订历史MediaWiki 1.43.8https://arolstar52-zhtest.hf.space/index.php?title=CD33&diff=3087881&oldid=previmported>曦城星月 来自 2025年8月19日 (二) 05:002025-08-19T05:00:08Z<p></p>
<p><b>新页面</b></p><div>{{Infobox_gene}}<br />
'''CD33'''或称为Siglec-3（唾液酸结合Ig-样凝集素3，SIGLEC3，SIGLEC-3，gp67，p67）化学式为：C<sub>4240</sub>H<sub>6678</sub>O<sub>1672</sub>N<sub>1024</sub>S<sub>24</sub><ref>{{Cite web |title=Expasy - ProtParam |url=https://web.expasy.org/cgi-bin/protparam/protparam_bis.cgi?P20138@18-364@ |website=web.expasy.org |access-date=2025-08-19}}</ref><ref>{{Cite web |title=UniProt |url=https://www.uniprot.org/uniprotkb/P20138/entry |website=UniProt |language=en |access-date=2025-08-19}}</ref>，是一个[[粒细胞]]系的细胞表面表达的[[細胞表面受體|跨膜受体]]<ref name="pmid15388576">{{Cite journal|title=Expression of the myeloid-associated marker CD33 is not an exclusive factor for leukemic plasmacytoid dendritic cells|url=http://www.bloodjournal.org/cgi/pmidlookup?view=long&pmid=15388576|date=Feb 2005|journal=Blood|issue=3|doi=10.1182/blood-2004-06-2416|volume=105|pages=1256–64|pmid=15388576|author=|access-date=2018-07-15|archive-url=https://web.archive.org/web/20190924183413/http://www.bloodjournal.org/content/105/3/1256.long?sso-checked=true|archive-date=2019-09-24|dead-url=yes}}</ref>。它通常被认为是髓源性细胞所特有的，但它也可以在一些[[淋巴系統|淋巴]]细胞上表达。<ref name="pmid16380601">{{Cite journal|title=A study of CD33 (SIGLEC-3) antigen expression and function on activated human T and NK cells: two isoforms of CD33 are generated by alternative splicing|url=http://www.jleukbio.org/cgi/pmidlookup?view=long&pmid=16380601|date=Jan 2006|journal=Journal of Leukocyte Biology|issue=1|doi=10.1189/jlb.0205096|volume=79|pages=46–58|pmid=16380601}}{{Dead link|date=2018年8月 |bot=InternetArchiveBot |fix-attempted=yes }}</ref><br />
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它能与唾液酸结合，因此属于[[凝集素]]中的[[SIGLEC]]家族。<br />
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== 参考文献 ==<br />
{{reflist|2}}<br />
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== 外部链接 ==<br />
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* {{UCSC gene info|CD33}}<br />
{{clusters of differentiation}}<br />
{{凝集素}}<br />
[[Category:位於19號人類染色體的基因]]<br />
[[Category:凝集素]]</div>imported>曦城星月