https://arolstar52-zhtest.hf.space/index.php?action=history&feed=atom&title=CD14 2026-07-16T17:42:48Z 在这个wiki上该页的修订历史 MediaWiki 1.43.9 https://arolstar52-zhtest.hf.space/index.php?title=CD14&diff=4355143&oldid=prev 2024-09-30T07:58:43Z

<p>// Edit via Wikiplus</p> <p><b>新页面</b></p><div>{{Expand English|date=2023-12-18}}<br /> {{Infobox_gene}}<br /> &#039;&#039;&#039;{{PAGENAME}}&#039;&#039;&#039;（cluster of differentiation 14，分化簇14）是一种细胞表面蛋白质，主要在[[先天免疫系統]]的[[巨噬细胞]]上表达&lt;ref name=&quot;pmid2472171&quot;&gt;{{cite journal | vauthors = Setoguchi M, Nasu N, Yoshida S, Higuchi Y, Akizuki S, Yamamoto S | title = Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones | journal = Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | volume = 1008 | issue = 2 | pages = 213–222 | date = July 1989 | pmid = 2472171 | doi = 10.1016/0167-4781(80)90012-3 }}&lt;/ref&gt;，是最早发现的[[模式识别受体]]&lt;ref name=&quot;pmid2462937&quot;&gt;{{cite journal | vauthors = Simmons DL, Tan S, Tenen DG, Nicholson-Weller A, Seed B | title = Monocyte antigen CD14 is a phospholipid anchored membrane protein | journal = Blood | volume = 73 | issue = 1 | pages = 284–289 | date = January 1989 | pmid = 2462937 | doi = 10.1182/blood.V73.1.284.284 | doi-access = free }}&lt;/ref&gt;，能参与识别[[脂多糖]]（LPS，一种[[病原相关分子模式]]）。<br /> <br /> [[Image:Toll-like receptor pathways revised.jpg|thumbnail|left|500px|CD14与[[TLR4]]等形成识别LPS的复合物]]<br /> {{clear}}<br /> ==参考文献==<br /> {{reflist}}<br /> ==外部链接==<br /> * {{UCSC gene info|CD14}}<br /> * {{PDBe-KB2|P08571|Monocyte differentiation antigen CD14}}<br /> * {{MeshName|CD14+Antigens}}<br /> {{Clusters of differentiation}}<br /> {{Clusters of differentiation by lineage}}<br /> {{TLR signaling pathway}}</div>

imported>Heihaheihaha