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CBD-DMH - 版本历史
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<p><b>新页面</b></p><div>{{Expand English|date=2023-06-29}}<br />
{{Drugbox<br />
| IUPAC_name = 5-(1,1-Dimethylheptyl)-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-1,3-benzenediol<br />
| image = CBD-DMH_structure.png<br />
| width = 220<br />
<br />
<!--Clinical data--><br />
| tradename =<br />
<br />
<!--Identifiers--><br />
| CAS_number_Ref = {{cascite|correct|CAS}}<br />
| CAS_number = 97452-63-6 <br />
| UNII_Ref = {{fdacite|correct|FDA}}<br />
| UNII = P28FSD6QS7<br />
| CAS_supplemental= (−)-enantiomer<br />
| PubChem = 126670<br />
| ChemSpiderID = 112525<br />
| StdInChI = 1S/C25H38O2/c1-7-8-9-10-13-25(5,6)19-15-22(26)24(23(27)16-19)21-14-18(4)11-12-20(21)17(2)3/h14-16,20-21,26-27H,2,7-13H2,1,3-6H3/t20-,21+/m0/s1<br />
| StdInChIKey = MPJURNPNPDQYSY-LEWJYISDSA-N<br />
<br />
<!--Chemical data--><br />
| C=25 | H=38 | O=2 <br />
| molecular_weight = 370.57<br />
| smiles = CCCCCCC(C)(C)c1cc(c(c(c1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O<br />
}}<br />
'''{{PAGENAMEBASE}}'''（大麻二酚-二甲基庚基，{{langx|en|Cannabidiol-dimethylheptyl}}，也缩写为'''DMH-CBD'''），分子式[[C25H38O2|C<sub>25</sub>H<sub>38</sub>O<sub>2</sub>]]，是一种人工合成的[[大麻素]]，可看做[[大麻二酚]]的[[同系物]]，其侧链上的[[戊基]]被替换成二甲基庚基。<ref>{{cite journal | vauthors = Leite JR, Carlini EA, Lander N, Mechoulam R | title = Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs | journal = Pharmacology | volume = 24 | issue = 3 | pages = 141–6 | year = 1982 | pmid = 7071126 | doi = 10.1159/000137588 }}</ref><ref>{{cite journal | vauthors = Bisogno T, Hanus L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, Moriello AS, Davis JB, Mechoulam R, Di Marzo V | display-authors = 6 | title = Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide | url = https://archive.org/details/sim_british-journal-of-pharmacology_2001-10_134_4/page/845 | journal = British Journal of Pharmacology | volume = 134 | issue = 4 | pages = 845–52 | date = October 2001 | pmid = 11606325 | pmc = 1573017 | doi = 10.1038/sj.bjp.0704327 }}</ref><ref>{{cite journal | vauthors = Ben-Shabat S, Hanus LO, Katzavian G, Gallily R | title = New cannabidiol derivatives: synthesis, binding to cannabinoid receptor, and evaluation of their antiinflammatory activity | journal = Journal of Medicinal Chemistry | volume = 49 | issue = 3 | pages = 1113–7 | date = February 2006 | pmid = 16451075 | doi = 10.1021/jm050709m }}</ref><ref>{{cite journal | vauthors = Juknat A, Kozela E, Kaushansky N, Mechoulam R, Vogel Z | title = Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - studies in BV-2 microglia and encephalitogenic T cells | journal = Journal of Basic and Clinical Physiology and Pharmacology | volume = 27 | issue = 3 | pages = 289–96 | date = May 2016 | pmid = 26540221 | doi = 10.1515/jbcpp-2015-0071 | doi-access = free }}</ref><br />
<br />
==参考文献==<br />
{{reflist}}<br />
<br />
==外部链接==<br />
{{大麻素}}<br />
<br />
[[Category:大麻素]]<br />
[[Category:環己烯]]</div>
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