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AM-905 - 版本历史
2026-07-15T19:33:59Z
在这个wiki上该页的修订历史
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2025-06-04T10:12:17Z
<p><a href="https://en.wikipedia.org/wiki/%E6%9C%BA%E5%99%A8%E4%BA%BA/%E4%BD%9C%E4%B8%9A%E8%AF%B7%E6%B1%82#.E8.AB.8B.E6.B1.82.E6.89.B9.E9.87.8F.E6.9B.BF.E6.8F.9B.E6.89.80.E6.9C.89lang-xx.E6.A8.A1.E6.9D.BF.E7.82.BAlangx.E6.A8.A1.E6.9D.BF" class="extiw" title="wikipedia:机器人/作业请求">BOTR</a>：批量替換所有lang-xx模板為langx模板</p>
<p><b>新页面</b></p><div>{{Expand English|date=2023-06-29}}<br />
{{Drugbox<br />
| verifiedrevid = 477235983<br />
| IUPAC_name = (6a''R'',9''R'',10a''R'')-3-[(''E'')-hept-1-enyl]-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[''c'']chromen-1-ol<br />
| image = AM-905.svg<br />
| width = 240<br />
<br />
<!--Clinical data--><br />
| tradename = <br />
| legal_status = <br />
| routes_of_administration =<br />
<br />
<!--Pharmacokinetic data--><br />
| metabolism = <br />
| elimination_half-life = <br />
| excretion =<br />
<br />
<!--Identifiers--><br />
| CAS_number_Ref = {{cascite|correct|??}}<br />
| CAS_number = 181139-62-8 <br />
| UNII_Ref = {{fdacite|correct|FDA}}<br />
| UNII = TJ6JD73J07<br />
| ChEMBL_Ref = {{ebicite|correct|EBI}}<br />
| ChEMBL = 127848<br />
| PubChem = 9998522<br />
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}<br />
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}<br />
| ChemSpiderID = 8174103<br />
<br />
<!--Chemical data--><br />
| C=23 | H=34 | O=3 <br />
| smiles = CCCCC/C=C/c(cc1O)cc(OC(C)(C)C2CC3)c1C2CC3CO<br />
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}<br />
| StdInChI = 1S/C23H34O3/c1-4-5-6-7-8-9-16-13-20(25)22-18-12-17(15-24)10-11-19(18)23(2,3)26-21(22)14-16/h8-9,13-14,17-19,24-25H,4-7,10-12,15H2,1-3H3/b9-8+/t17-,18-,19-/m1/s1<br />
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}<br />
| StdInChIKey = NJIKRWBGUIYKJM-OKMMTOMJSA-N<br />
}}<br />
'''{{PAGENAMEBASE}}'''（{{langx|en|AM-905}}），分子式[[C23H34O3|C<sub>23</sub>H<sub>34</sub>O<sub>3</sub>]]，是一种AM系[[大麻素]]，可作为[[镇痛药]]，其特点是侧链上存在与[[苯环]]共轭的碳碳[[双键]]，且为E构象<ref name="Busch-PetersenHill1996">{{cite journal | vauthors = Busch-Petersen J, Hill WA, Fan P, Khanolkar A, Xie XQ, Tius MA, Makriyannis A | title = Unsaturated side chain beta-11-hydroxyhexahydrocannabinol analogs | journal = Journal of Medicinal Chemistry | volume = 39 | issue = 19 | pages = 3790–6 | date = September 1996 | pmid = 8809166 | doi = 10.1021/jm950934b | authorlink7 = Alexandros Makriyannis }}</ref>。<br />
<br />
==另见==<br />
* [[AM-906]]，碳碳双键为Z构象的[[顺反异构体]]<br />
* [[HU-243]]，相同位置为[[偕]]二甲基，存在[[偕二甲基效应]]<br />
<br />
==参考文献==<br />
{{reflist}}<br />
<br />
==外部链接==<br />
{{大麻素}}<br />
<br />
[[Category:环己烷甲醇]]<br />
[[Category:苯酚]]</div>
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