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AM-11245 - 版本历史
2026-07-17T04:28:45Z
在这个wiki上该页的修订历史
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imported>Leiem 来自 2025年2月24日 (一) 03:35
2025-02-24T03:35:08Z
<p></p>
<p><b>新页面</b></p><div>{{Drugbox<br />
| IUPAC_name = 8-[(6aR,9R,10aR)-1-hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl]-8-methylnonanenitrile<br />
| image = AM-11245_structure.png<br />
| image_class = skin-invert-image<br />
| width = 240<br />
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<!--Clinical data--><br />
| tradename = <br />
| legal_status = <br />
| routes_of_administration = <br />
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<!--Pharmacokinetic data--><br />
| metabolism = <br />
| elimination_half-life =<br />
| excretion = <br />
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<!--Identifiers--><br />
| CAS_number_Ref = {{cascite|correct|CAS}}<br />
| CAS_number = 2762979-76-8<br />
| UNII = <br />
| ChEMBL = 5091754<br />
| PubChem = 166636133<br />
| ChemSpiderID = 129302120<br />
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<!--Chemical data--><br />
| C=26 | H=39 | N=1 | O=3 <br />
| smiles = CC1(C)OC2=C([C@H]3[C@H]1CC[C@@H](CO)C3)C(O)=CC(C(C)(C)CCCCCCC#N)=C2<br />
| StdInChI=1S/C26H39NO3/c1-25(2,12-8-6-5-7-9-13-27)19-15-22(29)24-20-14-18(17-28)10-11-21(20)26(3,4)30-23(24)16-19/h15-16,18,20-21,28-29H,5-12,14,17H2,1-4H3/t18-,20-,21-/m1/s1<br />
| StdInChIKey = IGSAQGJQMKOTAG-HMXCVIKNSA-N<br />
}}<br />
'''{{PAGENAME}}'''（化学名：3-(1,1-二甲基己基-6-氰基)-9-羟甲基六氢大麻酚）是一种含氮[[有机化合物]]，化学式[[C26H39NO3|{{chem2|C26H39NO3}}]]，属于一种[[AM大麻素列表|AM系列]][[大麻素]]<ref name="Jiang_2021">{{cite journal | vauthors = Jiang S, Iliopoulos-Tsoutsouvas C, Tong F, Brust CA, Keenan CM, Raghav JG, Hua T, Wu S, Ho JH, Wu Y, Grim TW, Zvonok N, Thakur GA, Liu ZJ, Sharkey KA, Bohn LM, Nikas SP, Makriyannis A | display-authors = 6 | title = Novel Functionalized Cannabinoid Receptor Probes: Development of Exceptionally Potent Agonists | journal = Journal of Medicinal Chemistry | volume = 64 | issue = 7 | pages = 3870–3884 | date = April 2021 | pmid = 33761251 | doi = 10.1021/acs.jmedchem.0c02053 | s2cid = 232355437 }}</ref>。它可以{{lwd|Q72467619}}和[[5-溴戊氧基苯]]为原料，经过多步反应，纯化后得到。<ref name="Jiang_2021" /><br />
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==参考文献==<br />
{{reflist}}<br />
<br />
[[Category:大麻素]]<br />
[[Category:苯并色烯]]<br />
[[Category:酚]]<br />
[[Category:腈]]</div>
imported>Leiem