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A-68930 - 版本历史
2026-07-19T17:07:15Z
本wiki上该页面的版本历史
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imported>Htmlzycq：使用HotCat已移除Category:氨乙基化合物; 已添加Category:氨甲基化合物
2025-09-01T12:38:26Z
<p>使用<a href="/index.php?title=WP:HOTCAT&action=edit&redlink=1" class="new" title="WP:HOTCAT（页面不存在）">HotCat</a>已移除<a href="/wiki/Category:%E6%B0%A8%E4%B9%99%E5%9F%BA%E5%8C%96%E5%90%88%E7%89%A9" title="Category:氨乙基化合物">Category:氨乙基化合物</a>; 已添加<a href="/wiki/Category:%E6%B0%A8%E7%94%B2%E5%9F%BA%E5%8C%96%E5%90%88%E7%89%A9" title="Category:氨甲基化合物">Category:氨甲基化合物</a></p>
<p><b>新页面</b></p><div>{{Chembox<br />
| Verifiedfields = changed<br />
| Watchedfields = changed<br />
| verifiedrevid = 477234941<br />
| ImageFile = A-68930 Structure.svg<br />
| ImageFile_Ref = {{chemboximage|correct|??}}<br />
| ImageSize =<br />
| ImageName = Stereo, Kekulé skeletal formula of A-68930<br />
| PIN = (1''R'',3''S'')-1-(Aminomethyl)-3-phenyl-3,4-dihydro-1''H''-2-benzopyran-5,6-diol<br />
|Section1={{Chembox Identifiers<br />
| IUPHAR_ligand = 6077<br />
| CASNo = 130465-45-1<br />
| CASNo_Ref = {{cascite|correct|CAS}}<br />
| CASNo2 = 130465-39-3<br />
| CASNo2_Ref = {{cascite|correct|}}<br />
| CASNo2_Comment = ([[hydrochloride|HCl]])<br />
| UNII_Ref = {{fdacite|correct|FDA}}<br />
| UNII = B4NI77O5D4<br />
| PubChem = 122324<br />
| ChemSpiderID = 109076<br />
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}<br />
| MeSHName = A+68930<br />
| ChEMBL = 315468<br />
| ChEMBL_Ref = {{ebicite|changed|EBI}}<br />
| SMILES = Oc1c(O)ccc2c1C[C@H](O[C@H]2CN)c3ccccc3<br />
| StdInChI = InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1<br />
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}<br />
| StdInChIKey = SUHGRZPINGKYNV-GJZGRUSLSA-N<br />
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}<br />
}}<br />
|Section2={{Chembox Properties<br />
| C=16 | H=17 | N=1 | O=3 <br />
| LogP = 1.175<br />
| pKa = 9.491<br />
| pKb = 4.506<br />
}}<br />
}}<br />
'''{{PAGENAME}}'''是一种人工合成的含氮[[有机化合物]]，化学式[[C16H17NO3|C<sub>16</sub>H<sub>17</sub>NO<sub>3</sub>]]，能作为[[多巴胺受體]][[多巴胺受體D1|D<sub>1</sub>]]的[[激动剂]]<ref name="pmid1977907">{{cite journal |vauthors =DeNinno MP, Schoenleber R, Asin KE, MacKenzie R, Kebabian JW |title=(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran: a potent and selective D1 agonist |journal=Journal of Medicinal Chemistry |volume=33 |issue=11 |pages=2948–50 |date=November 1990 |pmid=1977907 |doi= 10.1021/jm00173a005}}</ref><ref name="pmid1683288">{{cite journal |vauthors =DeNinno MP, Schoenleber R, MacKenzie R, Britton DR, Asin KE, Briggs C, Trugman JM, Ackerman M, Artman L, Bednarz L |title=A68930: a potent agonist selective for the dopamine D1 receptor |journal=European Journal of Pharmacology |volume=199 |issue=2 |pages=209–19 |date=June 1991 |pmid=1683288 |doi= 10.1016/0014-2999(91)90459-4}}</ref>。它可以{{WikidataLink|Q81988949}}和[[苯基环氧乙烷]]为原料经多步反应制得。<ref name="pmid1977907" /><br />
<br />
==参考文献==<br />
{{reflist}}<br />
<br />
==外部链接==<br />
<br />
{{organic-compound-stub}}<br />
<br />
[[Category:多巴胺受体D1激动剂]]<br />
[[Category:邻苯二酚]]<br />
[[Category:苯乙醇胺醚]]<br />
[[Category:氨甲基化合物]]</div>
imported>Htmlzycq