编辑“︁Template:PBB/7852”︁

{{GNF_Protein_box
 | Name = Chemokine (C-X-C motif) receptor 4
 | image = 3OE9_(CXCR4).png
 | image_source = CXCR4 in complex with IT1t(PDB {{PDB2|3OE9}})
 | PDB = {{PDB2|2K03}}, {{PDB2|2K04}}, {{PDB2|2K05}}, {{PDB2|3ODU}}, {{PDB2|3OE0}}, {{PDB2|3OE6}}, {{PDB2|3OE8}}, {{PDB2|3OE9}}
 | HGNCid = 2561
 | MGIid = 109563
 | Symbol = CXCR4
 | AltSymbols =; CD184; D2S201E; FB22; HM89; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM
 | IUPHAR = yes
 | ChEMBL = 2107
 | OMIM = 162643
 | ECnumber = 
 | Homologene = 20739
 | GeneAtlas_image1 = PBB_GE_CXCR4_217028_at_tn.png
 | GeneAtlas_image2 = PBB_GE_CXCR4_209201_x_at_tn.png
 | GeneAtlas_image3 = PBB_GE_CXCR4_211919_s_at_tn.png
 | Protein_domain_image = 
 | Function = {{GNF_GO|id=GO:0003779 |text = actin binding}} {{GNF_GO|id=GO:0004930 |text = G-protein coupled receptor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0015026 |text = coreceptor activity}} {{GNF_GO|id=GO:0016494 |text = C-X-C chemokine receptor activity}} {{GNF_GO|id=GO:0019958 |text = C-X-C chemokine binding}} {{GNF_GO|id=GO:0031625 |text = ubiquitin protein ligase binding}} {{GNF_GO|id=GO:0032027 |text = myosin light chain binding}} {{GNF_GO|id=GO:0043130 |text = ubiquitin binding}}
 | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0009897 |text = external side of plasma membrane}} {{GNF_GO|id=GO:0009986 |text = cell surface}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} {{GNF_GO|id=GO:0016023 |text = cytoplasmic membrane-bounded vesicle}} {{GNF_GO|id=GO:0030426 |text = growth cone}} {{GNF_GO|id=GO:0031252 |text = cell leading edge}} {{GNF_GO|id=GO:0031410 |text = cytoplasmic vesicle}}
 | Process = {{GNF_GO|id=GO:0000187 |text = activation of MAPK activity}} {{GNF_GO|id=GO:0001569 |text = patterning of blood vessels}} {{GNF_GO|id=GO:0001666 |text = response to hypoxia}} {{GNF_GO|id=GO:0001667 |text = ameboidal cell migration}} {{GNF_GO|id=GO:0001764 |text = neuron migration}} {{GNF_GO|id=GO:0002407 |text = dendritic cell chemotaxis}} {{GNF_GO|id=GO:0006915 |text = apoptotic process}} {{GNF_GO|id=GO:0006954 |text = inflammatory response}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor signaling pathway}} {{GNF_GO|id=GO:0007204 |text = elevation of cytosolic calcium ion concentration}} {{GNF_GO|id=GO:0007281 |text = germ cell development}} {{GNF_GO|id=GO:0007420 |text = brain development}} {{GNF_GO|id=GO:0008045 |text = motor neuron axon guidance}} {{GNF_GO|id=GO:0008354 |text = germ cell migration}} {{GNF_GO|id=GO:0009615 |text = response to virus}} {{GNF_GO|id=GO:0016032 |text = viral reproduction}} {{GNF_GO|id=GO:0019048 |text = virus-host interaction}} {{GNF_GO|id=GO:0019722 |text = calcium-mediated signaling}} {{GNF_GO|id=GO:0022415 |text = viral reproductive process}} {{GNF_GO|id=GO:0030260 |text = entry into host cell}} {{GNF_GO|id=GO:0030334 |text = regulation of cell migration}} {{GNF_GO|id=GO:0042098 |text = T cell proliferation}} {{GNF_GO|id=GO:0042119 |text = neutrophil activation}} {{GNF_GO|id=GO:0043217 |text = myelin maintenance}} {{GNF_GO|id=GO:0048714 |text = positive regulation of oligodendrocyte differentiation}} {{GNF_GO|id=GO:0050920 |text = regulation of chemotaxis}} {{GNF_GO|id=GO:0061351 |text = neural precursor cell proliferation}}
 | Hs_EntrezGene = 7852
 | Hs_Ensembl = ENSG00000121966
 | Hs_RefseqmRNA = NM_001008540
 | Hs_RefseqProtein = NP_001008540
 | Hs_GenLoc_db = hg19
 | Hs_GenLoc_chr = 2
 | Hs_GenLoc_start = 136871919
 | Hs_GenLoc_end = 136875735
 | Hs_Uniprot = P61073
 | Mm_EntrezGene = 12767
 | Mm_Ensembl = ENSMUSG00000045382
 | Mm_RefseqmRNA = NM_009911
 | Mm_RefseqProtein = NP_034041
 | Mm_GenLoc_db = mm9
 | Mm_GenLoc_chr = 1
 | Mm_GenLoc_start = 128588199
 | Mm_GenLoc_end = 128592293
 | Mm_Uniprot = P70658
 | path = PBB/7852
}}