编辑“︁Template:PBB/1565”︁

{{GNF_Protein_box
 | Name = Cytochrome P450, family 2, subfamily D, polypeptide 6
 | image = CYP2D6_structure.png
 | image_source = [[Protein_Data_Bank|PDB]]基于2f9q的渲染图
 | PDB = {{PDB2|2F9Q}}, {{PDB2|3QM4}}, {{PDB2|3TBG}}, {{PDB2|3TDA}}, {{PDB2|4WNT}}, {{PDB2|4WNU}}, {{PDB2|4WNV}}, {{PDB2|4WNW}}
 | HGNCid = 2625
 | MGIid = 1929474
 | Symbol = CYP2D6
 | AltSymbols =; CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; P450-DB1; P450C2D; P450DB1
 | IUPHAR = 
 | ChEMBL = 
 | OMIM = 124030
 | ECnumber = 1.14.14.1
 | Homologene = 133550
 | GeneAtlas_image1 = PBB_GE_CYP2D6_207498_s_at_tn.png
 | GeneAtlas_image2 = PBB_GE_CYP2D6_215809_at_tn.png
 | GeneAtlas_image3 = 
 | Protein_domain_image = 
 | Function = {{GNF_GO|id=GO:0004497 |text = monooxygenase activity}} {{GNF_GO|id=GO:0005506 |text = iron ion binding}} {{GNF_GO|id=GO:0008144 |text = drug binding}} {{GNF_GO|id=GO:0008392 |text = arachidonic acid epoxygenase activity}} {{GNF_GO|id=GO:0008395 |text = steroid hydroxylase activity}} {{GNF_GO|id=GO:0016491 |text = oxidoreductase activity}} {{GNF_GO|id=GO:0016712 |text = oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen}} {{GNF_GO|id=GO:0019825 |text = oxygen binding}} {{GNF_GO|id=GO:0020037 |text = heme binding}} {{GNF_GO|id=GO:0070330 |text = aromatase activity}}
 | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005739 |text = mitochondrion}} {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0005789 |text = endoplasmic reticulum membrane}}
 | Process = {{GNF_GO|id=GO:0006805 |text = xenobiotic metabolic process}} {{GNF_GO|id=GO:0008202 |text = steroid metabolic process}} {{GNF_GO|id=GO:0009804 |text = coumarin metabolic process}} {{GNF_GO|id=GO:0009820 |text = alkaloid metabolic process}} {{GNF_GO|id=GO:0009822 |text = alkaloid catabolic process}} {{GNF_GO|id=GO:0016098 |text = monoterpenoid metabolic process}} {{GNF_GO|id=GO:0017144 |text = drug metabolic process}} {{GNF_GO|id=GO:0019369 |text = arachidonic acid metabolic process}} {{GNF_GO|id=GO:0033076 |text = isoquinoline alkaloid metabolic process}} {{GNF_GO|id=GO:0042737 |text = drug catabolic process}} {{GNF_GO|id=GO:0042738 |text = exogenous drug catabolic process}} {{GNF_GO|id=GO:0044281 |text = small molecule metabolic process}} {{GNF_GO|id=GO:0046483 |text = heterocycle metabolic process}} {{GNF_GO|id=GO:0051100 |text = negative regulation of binding}} {{GNF_GO|id=GO:0055114 |text = oxidation-reduction process}} {{GNF_GO|id=GO:0070989 |text = oxidative demethylation}} {{GNF_GO|id=GO:0090350 |text = negative regulation of cellular organofluorine metabolic process}}
 | Hs_EntrezGene = 1565
 | Hs_Ensembl = ENSG00000100197
 | Hs_RefseqmRNA = NM_000106
 | Hs_RefseqProtein = NP_000097
 | Hs_GenLoc_db = hg38
 | Hs_GenLoc_chr = 22
 | Hs_GenLoc_start = 42126499
 | Hs_GenLoc_end = 42130906
 | Hs_Uniprot = P10635
 | Mm_EntrezGene = 13101
 | Mm_Ensembl = ENSMUSG00000094806
 | Mm_RefseqmRNA = NM_010005
 | Mm_RefseqProtein = NP_034135
 | Mm_GenLoc_db = 
 | Mm_GenLoc_chr = 15
 | Mm_GenLoc_start = 82402846
 | Mm_GenLoc_end = 82407194
 | Mm_Uniprot = P24456
 | path = PBB/1565
}}