编辑“︁MYO1F”︁

{{Infobox_gene}}
'''''MYO1F''''' (化学式为：C<sub>5543</sub>H<sub>8726</sub>O<sub>1622</sub>N<sub>1590</sub>S<sub>39</sub><ref>{{Cite web |title=Expasy - ProtParam |url=https://web.expasy.org/cgi-bin/protparam/protparam_bis.cgi?O00160@1-1098@ |website=web.expasy.org |access-date=2026-02-13}}</ref>)是一个位于[[17號染色體|人类17号染色体]]上的基因，該编码是一种隶属於[[肌凝蛋白]][[蛋白質超家族|超家族]]的蛋白肌凝蛋白-If（{{lang|en|Myosin-If}}）。''MYO1F''编码的肌凝蛋白-If是一种非典型的[[肌凝蛋白]]，与编码肌凝蛋白-1''[[MYH1]]''是两种不同的基因。<ref>{{cite web |title=MYO1F Gene |url=https://www.genecards.org/cgi-bin/carddisp.pl?gene=MYO1F |website=GeneCards |accessdate=2021-05-02 |archive-date=2021-06-04 |archive-url=https://web.archive.org/web/20210604205137/https://www.genecards.org/cgi-bin/carddisp.pl?gene=MYO1F }}</ref><ref name="pmid9119401">{{cite journal |vauthors=Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C | title = Cloning of the genes encoding two murine and human cochlear unconventional type I myosins | journal = Genomics | volume = 40 | issue = 2 | pages = 332–41 |date=Apr 1997 | pmid = 9119401 | doi =10.1006/geno.1996.4526  }}</ref><ref name="pmid8884266">{{cite journal |vauthors=Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA | title = Mapping of unconventional myosins in mouse and human | journal = Genomics | volume = 36 | issue = 3 | pages = 431–9 |date=Feb 1997 | pmid = 8884266 | doi = 10.1006/geno.1996.0488 }}</ref><ref name="entrez">{{cite web| title = Entrez Gene: MYO1F myosin IF| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4542| access-date = 2021-05-02| archive-date = 2010-12-05| archive-url = https://web.archive.org/web/20101205081110/http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene}}</ref>

''MYO1F''基因主要在[[免疫系统]]中表达，其功能主要與细胞黏附，细胞移动有關<ref name="pmid17023661">{{cite journal |vauthors=Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA | title = Modulation of cell adhesion and motility in the immune system by Myo1f |url=https://archive.org/details/sim_science_2006-10-06_314_5796/page/136 | journal = Science | volume = 314 | issue = 5796 | pages = 136–9 |date=October 2006 | pmid = 17023661 | doi = 10.1126/science.1131920}}</ref>。而该基因的突变則与非综合征性[[耳聋]]有关<ref name="pmid11493199">{{cite journal |vauthors=Chen AH, Stephan DA, Hasson T, Fukushima K, Nelissen CM, Chen AF, Jun AI, Ramesh A, Van Camp G, Smith RJ | title = MYO1F as a candidate gene for nonsyndromic deafness, DFNB15 | journal = Arch. Otolaryngol. Head Neck Surg. | volume = 127 | issue = 8 | pages = 921–5 |date=August 2001 | pmid = 11493199 | doi = 10.1001/archotol.127.8.921}}</ref>。

==参见==
*[[肌凝蛋白]]

==参考资料==
{{reflist}}

==拓展阅读==
{{refbegin | 2}}
*{{cite journal   |vauthors=Bement WM, Hasson T, Wirth JA, etal |title=Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 14 |pages= 6549–53 |year= 1994 |pmid= 8022818 |doi=10.1073/pnas.91.14.6549  | pmc=44240  }}
*{{cite journal   |vauthors=Krugmann S, Anderson KE, Ridley SH, etal |title=Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices |journal=Mol. Cell |volume=9 |issue= 1 |pages= 95–108 |year= 2002 |pmid= 11804589 |doi=10.1016/S1097-2765(02)00434-3  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285}}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |url=https://archive.org/details/sim_nature-uk_2005-10-20_437_7062/page/1172 |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
{{refend}}
{{细胞骨架蛋白}}
{{biochem-stub}}

[[Category:细胞骨架]]