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CXCR3
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== 疾病 == CXCR3可能在下列疾病中起作用,包括[[动脉粥样硬化]]<ref>{{cite journal | last1=Mach | first1=F. | last2=Sauty | first2=A. | last3=Iarossi | first3=A. S. | last4=Sukhova | first4=G. K. | last5=Neote | first5=K. | last6=Libby | first6=P. | last7=Luster | first7=A. D. | title=Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells | url=https://archive.org/details/sim_journal-of-clinical-investigation_1999-10_104_8/page/1040 | journal=The Journal of Clinical Investigation | volume=104 | issue=8 | date=1999 | issn=0021-9738 | pmid=10525042 | pmc=408576 | doi=10.1172/JCI6993 | doi-access=free | pages=1041–1050 }}</ref>、[[多发性硬化]]<ref>{{cite journal | last1=Sørensen | first1=T. L. | last2=Tani | first2=M. | last3=Jensen | first3=J. | last4=Pierce | first4=V. | last5=Lucchinetti | first5=C. | last6=Folcik | first6=V. A. | last7=Qin | first7=S. | last8=Rottman | first8=J. | last9=Sellebjerg | first9=F. | last10=Strieter | first10=R. M. | last11=Frederiksen | first11=J. L. | last12=Ransohoff | first12=R. M. | title=Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients | url=https://archive.org/details/sim_journal-of-clinical-investigation_1999-03_103_6/page/806 | journal=The Journal of Clinical Investigation | volume=103 | issue=6 | date=1999 | issn=0021-9738 | pmid=10079101 | pmc=408141 | doi=10.1172/JCI5150 | doi-access=free | pages=807–815}}</ref>、[[肺纤维化]]<ref>{{cite journal | last1=Jiang | first1=Dianhua | last2=Liang | first2=Jiurong | last3=Hodge | first3=Jennifer | last4=Lu | first4=Bao | last5=Zhu | first5=Zhou | last6=Yu | first6=Shuang | last7=Fan | first7=Juan | last8=Gao | first8=Yunfei | last9=Yin | first9=Zhinan | last10=Homer | first10=Robert | last11=Gerard | first11=Craig | last12=Noble | first12=Paul W. | title=Regulation of pulmonary fibrosis by chemokine receptor CXCR3 | url=https://archive.org/details/sim_journal-of-clinical-investigation_2004-07_114_2/page/290 | journal=The Journal of Clinical Investigation | volume=114 | issue=2 | date=2004 | issn=0021-9738 | pmid=15254596 | pmc=449741 | doi=10.1172/JCI16861 | doi-access=free | pages=291–299}}</ref>、I型[[糖尿病]]<ref>{{cite journal | last1=Frigerio | first1=Simona | last2=Junt | first2=Tobias | last3=Lu | first3=Bao | last4=Gerard | first4=Craig | last5=Zumsteg | first5=Urs | last6=Holländer | first6=Georg A. | last7=Piali | first7=Luca | title=Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis | journal=Nature Medicine | volume=8 | issue=12 | date=2002 | issn=1078-8956 | pmid=12415259 | doi=10.1038/nm1202-792 | pages=1414–1420 }}</ref>、重症肌无力、急性心脏移植排斥<ref>{{cite journal | last1=Hancock | first1=W. W. | last2=Lu | first2=B. | last3=Gao | first3=W. | last4=Csizmadia | first4=V. | last5=Faia | first5=K. | last6=King | first6=J. A. | last7=Smiley | first7=S. T. | last8=Ling | first8=M. | last9=Gerard | first9=N. P. | last10=Gerard | first10=C. | title=Requirement of the chemokine receptor CXCR3 for acute allograft rejection | journal=The Journal of Experimental Medicine | volume=192 | issue=10 | date=2000-11-20 | issn=0022-1007 | pmid=11085753 | pmc=2193193 | doi=10.1084/jem.192.10.1515 | doi-access=free | pages=1515–1520 }}</ref>。开发阻断CXCR3与其配体相互作用的药物可提供治疗这些疾病的新途径。
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